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Clin Exp Rheumatol ; 14(6): 649-52, 1996.
Artigo em Inglês | MEDLINE | ID: mdl-8978960

RESUMO

OBJECTIVE: A non-invasive imaging technique (laser Doppler perfusion imaging-LDI) based on measurement of backscattered Doppler-broadened near infra-red laser radiation was used to provide two-dimensional images of perfusion over the proximal interphalangeal (PIP) joints of a group of normal subjects compared to a group of patients with rheumatoid arthritis (RA). RESULTS: Some PIP joints of the RA group showed areas of increased perfusion whereas normal subjects showed much less variation in perfusion between joints. These hyperaemic areas arose from the underlying joint, as scans taken with a less penetrating red laser did not show such areas. CONCLUSION: Apart from its obvious dermatological uses, LDI could be employed to image hyperaemia associated with a variety of inflammatory conditions affecting subcutaneous structures.


Assuntos
Artrite Reumatoide/fisiopatologia , Articulações dos Dedos/irrigação sanguínea , Fluxometria por Laser-Doppler/métodos , Adulto , Velocidade do Fluxo Sanguíneo , Feminino , Humanos , Processamento de Imagem Assistida por Computador , Masculino , Pessoa de Meia-Idade
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