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1.
An Sist Sanit Navar ; 42(2): 77154, 2019 12 27.
Artigo em Espanhol | MEDLINE | ID: mdl-31880297

RESUMO

This corrects the authors listed in "Takotsubo syndrome and hyperthyroidism: a case report" published in volume 42(2) pages 215-220, doi: 10.23938/ASSN.0713.

2.
An Sist Sanit Navar ; 42(2): 215-220, 2019 08 23.
Artigo em Espanhol | MEDLINE | ID: mdl-31343641

RESUMO

Stress cardiomyopathy, or Takotsubo syndrome, is similar to that of an acute coronary syndrome, with electrocardiographic changes and an increase in troponin levels; however, coronary arteriography typically shows no obstructive lesions. One of the characteristic patterns are regional wall motion abnormalities identified by echocardiography. It has been described in association with thyroid disorders, although the causal mechanism is not clearly established. We present the case of a woman with acute chest pain and electrical and analytical changes. A severe ventricular dysfunction was observed but the coronary tree was free of lesions, all of which was compatible with a stress cardiomyopathy. Hyperthyroidism due to Graves' disease was observed as a trigger. The identification and management of clinical factors that might predispose patients to Takotsubo syndrome or impact on subsequent clinical outcome is mandatory.


Assuntos
Doença de Graves/complicações , Hipertireoidismo/complicações , Cardiomiopatia de Takotsubo/diagnóstico , Dor no Peito/etiologia , Ecocardiografia , Feminino , Humanos , Hipertireoidismo/etiologia , Pessoa de Meia-Idade , Cardiomiopatia de Takotsubo/etiologia
3.
Clin. transl. oncol. (Print) ; 20(6): 740-744, jun. 2018. tab, graf
Artigo em Inglês | IBECS | ID: ibc-173622

RESUMO

Purpose: Anti-thyroglobulin antibodies (TgAb) can be used as a surrogate tumor marker in the follow-up of papillary thyroid carcinoma (PTC). We try to determine if the change in TgAb levels in the first post-operative year is a good predictor of persistence/recurrence risk in TgAb-positive PTC patients. Methods/patients: 105 patients with PTC who underwent thyroidectomy between 1988 and 2014 were enrolled. We calculated the percentage of change in TgAb levels with the first measurement at 1-2 months after surgery and the second one at 12-14 months. Results: TgAb negativization was observed in 29 patients (27.6%), a decrease of more than 50% was observed in 57 patients (54.3%), less than 50% in 12 patients (11.4%) and in 7 patients (6.7%) the TgAb level had increased. The percentage of persistence/recurrence was 0, 8.8, 16.7 and 71.4% in each group, respectively (p < 0.001). In the multivariate analysis, only the percentage of change in TgAb showed a significant association with the risk of persistence/recurrence, regardless of other factors such as age, size and TNM stages. Conclusions: Changes in TgAb levels in the first year after surgery can predict the risk of persistence/recurrence of TgAb-positive PTC patients. Patients who achieved negativization of TgAb presented an excellent prognosis


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Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Neoplasias da Glândula Tireoide/patologia , Tireoidectomia/estatística & dados numéricos , Carcinoma Papilar/patologia , Tireoglobulina/antagonistas & inibidores , Neoplasias da Glândula Tireoide/cirurgia , Imunoglobulinas Estimuladoras da Glândula Tireoide/análise , Carcinoma Papilar/cirurgia , Testes de Função Tireóidea/estatística & dados numéricos , Biomarcadores Tumorais/análise , Estudos Retrospectivos , Resultado do Tratamento
4.
Clin Transl Oncol ; 20(6): 740-744, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29071517

RESUMO

PURPOSE: Anti-thyroglobulin antibodies (TgAb) can be used as a surrogate tumor marker in the follow-up of papillary thyroid carcinoma (PTC). We try to determine if the change in TgAb levels in the first post-operative year is a good predictor of persistence/recurrence risk in TgAb-positive PTC patients. METHODS/PATIENTS: 105 patients with PTC who underwent thyroidectomy between 1988 and 2014 were enrolled. We calculated the percentage of change in TgAb levels with the first measurement at 1-2 months after surgery and the second one at 12-14 months. RESULTS: TgAb negativization was observed in 29 patients (27.6%), a decrease of more than 50% was observed in 57 patients (54.3%), less than 50% in 12 patients (11.4%) and in 7 patients (6.7%) the TgAb level had increased. The percentage of persistence/recurrence was 0, 8.8, 16.7 and 71.4% in each group, respectively (p < 0.001). In the multivariate analysis, only the percentage of change in TgAb showed a significant association with the risk of persistence/recurrence, regardless of other factors such as age, size and TNM stages. CONCLUSIONS: Changes in TgAb levels in the first year after surgery can predict the risk of persistence/recurrence of TgAb-positive PTC patients. Patients who achieved negativization of TgAb presented an excellent prognosis.


Assuntos
Autoanticorpos/sangue , Biomarcadores Tumorais/análise , Carcinoma Papilar/patologia , Recidiva Local de Neoplasia/diagnóstico , Neoplasias da Glândula Tireoide/patologia , Tireoidectomia/mortalidade , Autoanticorpos/imunologia , Carcinoma Papilar/sangue , Carcinoma Papilar/imunologia , Carcinoma Papilar/cirurgia , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/sangue , Recidiva Local de Neoplasia/imunologia , Período Pós-Operatório , Prognóstico , Estudos Retrospectivos , Taxa de Sobrevida , Testes de Função Tireóidea , Neoplasias da Glândula Tireoide/sangue , Neoplasias da Glândula Tireoide/imunologia , Neoplasias da Glândula Tireoide/cirurgia
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