1.
Org Lett
; 9(6): 1033-6, 2007 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17311391
RESUMO
The tetracyclic fused polyether core of the marine natural product hemibrevetoxin B has been prepared in an efficient manner by using a strategy in which ring-closing metathesis (RCM) reactions were employed for ring synthesis. Simultaneous construction of the A and D rings was accomplished by double two-directional RCM of a tetraene. [reaction: see text]