[Evaluation of the existing sterilization regimens for dishware and fluids by the autoclaving method]. / Otsenka sushchestvuiushchikh rezhimov sterilizatsii posudy i zhidkostei metodom avtoklavirovaniia.

Analysis of the present conditions for autoclave sterilization of laboratory glassware and nutrient media showed that they were not well founded and that the assembly diagrams of the autoclaves did not meet the requirements to the apparatus providing aseptic conditions. Checking of the temperature fields revealed "week" points with respect to sterilization. The heating rate of the glassware and nutrient media was determined and the choice of the limiting point for the control of sterilization temperature in autoclaves was substantiated.

[Device for sampling and feeding under aseptic conditions]. / Ustroistvo dlia otbora prob i vvedeniia dobavok v asepticheskikh usloviiakh.

The scheme and operating principle of a device for sampling and feeding under aseptic conditions are discussed. The device provides sterility of the elements used for sampling and feeding and excludes the contact of the liquids with the environment. The results of the study on the device temperature fields substantiated the sterilization regime using the parameter of the aseptic efficient. The sterilization period is 10 minutes which decreases the steam consumption and increases the production efficiency.

[Collector device for apparatus hookup connections in microbiological manufacture]. / Kollektornoe ustroistvo montazhnykh skhem apparatov mikrobiologicheskikh proizvodstv.

A collector device developed on the basis of a holding tank is discussed. The working principle of the device, its characteristics and advantages as applied to microbiological industry are described. The use of the collector devices in the assembly diagrams of the apparatus provides reduction of the number of the piping fittings, the pipe-line length, the number of the sealing elements, heat evolution into the environment, and time of the apparatus servicing.

[Control over bellows tightness in the hermetic sealing subassemblies of equipment used in the technology of microbiological manufactures]. / Kontrol' germetichnosti sil'fonov uzlov germetizatsii oborudovaniia, ispol'zuemogo v tekhnologii mikrobiologicheskikh proizvodstv.

A universal procedure for controlling the sylphon hermeticity is discussed. Travelling sylphon or membrane diaphragms in combination with a dublicate sylphon are used as a separating element at the border of the separating media, e. g. the medium transporting through the valve and the environmental air. Pneumatic pressure higher than the working pressure of the separating medium is created inside the space between the working and the dublicate sylphons. If the hermeticity of one of the above sylphons is broken, the excessive pressure inside the space between them is reduced which is automatically stated by means of a pneumatic probe. Because of detection of the breach in the hermeticity of one of the sylphons in proper time, when the second sylphon is safe, the contact of the transporting medium with the environmental air is prevented. The described procedure for controlling the hermeticity is universal since it provides the use of the probes working only under the pressure independent of the type and physico-chemical properties of the separating medium. One of the important advantages of the new procedure is also the fact that the working sylphon appears to be empty since the outer with respect to it pressure of the separating medium is practically balanced by the pressure created in the sylphon space.