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Nucleic Acids Res ; 52(D1): D1683-D1693, 2024 Jan 05.
Artigo em Inglês | MEDLINE | ID: mdl-37889052

RESUMO

The UniLectin portal (https://unilectin.unige.ch/) was designed in 2019 with the goal of centralising curated and predicted data on carbohydrate-binding proteins known as lectins. UniLectin is also intended as a support for the study of lectomes (full lectin set) of organisms or tissues. The present update describes the inclusion of several new modules and details the latest (https://unilectin.unige.ch/humanLectome/), covering our knowledge of the human lectome and comprising 215 unevenly characterised lectins, particularly in terms of structural information. Each HumanLectome entry is protein-centric and compiles evidence of carbohydrate recognition domain(s), specificity, 3D-structure, tissue-based expression and related genomic data. Other recent improvements regarding interoperability and accessibility are outlined.


Assuntos
Bases de Dados de Proteínas , Lectinas , Humanos , Carboidratos/química , Lectinas/química , Ligação Proteica , Domínios Proteicos , Anotação de Sequência Molecular
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