RESUMO
Fifteen children, 6-14 years old, who were heavily exposed to pigeon droppings, presented with cough, chills and breathlessnes on mild exertion. Twelve gave immediate positive skin test reactions to pigeon droppings. Ten of the fifteen also gave a late (Arthus) reaction, and seven gave a positive delayed reaction which was maximal at 24--72 hr. Nine children had precipitins against avian droppings. In ten patients who were tested for lymphocyte transformation, five gave positive responses to both serum and pigeon droppings. Radiological findings of the chest showed parenchymatous infiltrations and diffuse interstitial reticulations, suggestive of extrinsic allergic alveolitis. In a control group of fifteen heavily-exposed children who had no symptoms, immediate and late skin reactions occurred respectively in five and two. One only had a positive precipitin test, and one of five tested had a positive lymphoblastic transformation. In a non-exposed comparable group of children, all tests were negative except for one immediate positive skin response. Children heavily exposed to the inhalation of avian antigens can develop extrinsic allergic bronchiolo-alveolitis.
Assuntos
Alveolite Alérgica Extrínseca/diagnóstico , Adolescente , Animais , Testes de Provocação Brônquica , Galinhas , Criança , Columbidae , Feminino , Humanos , Pulmão/diagnóstico por imagem , Ativação Linfocitária , Masculino , Precipitinas , Radiografia , Testes CutâneosRESUMO
Amniotic fluid total lipids (T.L.), lipid phosphorus (L.Ph.), phospholipids (Ph.L.), total cholesterol (T.Ch.), total proteins (T.P.) and inorganic phosphorus (I.Ph) were determined in a number of high risk pregnancies and compared to parallel data obtained for full term normal pregnancies. Amniotic fluid T.L., L.Ph., Ph.L. and T.Ch. were significantly decreased in diabetic and toxaemic cases. The decrement in L.Ph. and Ph.L. was more pronounced in diabetic and toxaemic mothers who delivered either still-births or neonates suffering from RDS or in cases of intrapartum death. The L.Ph. and Ph.L. were increased in case of toxaemic mothers who delivered living neonates with no RDS. In spite of the increase in T.Ch. in the same cases; the ratio of T.Ch to T.L. was constant except in cases with prolonged intrauterine foetal death where it was increased.
Assuntos
Líquido Amniótico/análise , Lipídeos/análise , Pré-Eclâmpsia/metabolismo , Gravidez em Diabéticas/metabolismo , Proteínas/análise , Colesterol/análise , Feminino , Morte Fetal/metabolismo , Humanos , Recém-Nascido , Fosfolipídeos/análise , Fósforo/análise , Gravidez , Síndrome do Desconforto Respiratório do Recém-Nascido/metabolismoRESUMO
Total lipids, total cholesterol, phospholipids and inorganic phosphorus were determined in the amniotic fluid of 36 normal and 12 premature neonates. Total lipids, phospholipids and cholesterol were significantly decreased in the premature patients and the extent of decrease was more pronounced in patients who developed respiratory distress syndrome. On the other hand, inorganic phosphorus content of the amniotic fluid was within the normal range.
