RESUMO
AIM: This prospective study was designed to assess the utility of the dual time point imaging technique using 2-[(18)F]-fluoro-2-deoxy-D-glucose (FDG) positron-emission tomography/computed tomography (PET/CT) to detect primary breast cancer and to determine whether it is useful for the detection of small and non-invasive cancers, as well as cancers in dense breast tissue. METHODS: One hundred and eleven patients with newly diagnosed breast cancer underwent two sequential PET/CT examinations (dual time point imaging) for preoperative staging. The maximum standardized uptake value (SUVmax) of FDG was measured from both time points. The percentage change in SUVmax (DeltaSUVmax%) between time points 1 (SUVmax1) and 2 (SUVmax2) was calculated. The patients were divided into groups: invasive (n=82), non invasive (n=29); large (>10mm; n=80), small (Assuntos
Neoplasias da Mama/diagnóstico por imagem
, Adulto
, Idoso
, Neoplasias da Mama/patologia
, Carcinoma Ductal de Mama/diagnóstico por imagem
, Carcinoma Ductal de Mama/patologia
, Carcinoma Intraductal não Infiltrante/diagnóstico por imagem
, Carcinoma Intraductal não Infiltrante/patologia
, Carcinoma Lobular/diagnóstico por imagem
, Carcinoma Lobular/patologia
, Feminino
, Fluordesoxiglucose F18
, Humanos
, Interpretação de Imagem Assistida por Computador/métodos
, Pessoa de Meia-Idade
, Invasividade Neoplásica
, Tomografia por Emissão de Pósitrons/métodos
, Estudos Prospectivos
, Compostos Radiofarmacêuticos
, Sensibilidade e Especificidade
, Tomografia Computadorizada por Raios X/métodos
