RESUMO
The Risk of Malignancy Index (RMI) is used for the prediction of ovarian malignancy. It includes menopausal status, carbohydrate antigen 125 serum levels, and ultrasound criteria. Three-dimensional power Doppler (3-DPD) is a reproducible investigation for assessment of tumor vascularity, classifying vascularity to avascular, parallel, and chaotic patterns. In this study; 3-DPD was added to RMI for prediction of malignancy in 400 cases of ovarian masses. Sensitivity of RMI for prediction of malignancy was 88%, with a cutoff value of 202.5 at 95% confidence interval. Sensitivity of 3-DPD for prediction of malignancy was 75%, adding 3-DPD to RMI increased its sensitivity to 99%. Considering the pilot nature of the study, further studies are needed to corroborate such findings.
Assuntos
Antígeno Ca-125/sangue , Neovascularização Patológica/sangue , Neovascularização Patológica/diagnóstico por imagem , Neoplasias Ovarianas/irrigação sanguínea , Ultrassonografia Doppler , Adenocarcinoma de Células Claras/irrigação sanguínea , Adenocarcinoma Mucinoso/irrigação sanguínea , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Carcinoma Papilar/irrigação sanguínea , Criança , Cistadenocarcinoma Seroso/irrigação sanguínea , Diagnóstico Diferencial , Feminino , Humanos , Imageamento Tridimensional , Menopausa , Pessoa de Meia-Idade , Prognóstico , Sensibilidade e Especificidade , Adulto JovemRESUMO
A comparative study of the intrinsic innervation in desert rodents (kangaroo rats) and others (albino rats) was carried out in an attempt to understand the functional anatomy of the bladder in these animals which are known to sustain severe water restraint. The bladder of the albino rat was innervated by predominantly thin nerves, more numerous beaded endings and few ganglia. That of the kangaroo rat had more numerous thick nerves (pre-ganglionic), large verve trunks, and ganglia which were extensively distributed in the wall. These findings indicate that the bladder of the albino rat depends mainly on the intrinsic innervation and facilatory micturition reflexes, while that of the kangaroo rat is intrinsically regulated, depending on a short neuron system. It was concluded that all the structural differences found might be essential for constant urine retention.