Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Epilepsy Behav ; 80: 272-279, 2018 03.
Artigo em Inglês | MEDLINE | ID: mdl-29398625

RESUMO

OBJECTIVE: Variable degrees of cognitive dysfunction have been reported in children with benign childhood epilepsy with centrotemporal spikes (BCECTS). Our aim was to perform quantitative analyses of the brain responses to cognitive tasks using event-related desynchronization (ERD) and event-related synchronization (ERS) and correlating the results with the scores of neuropsychological tests in patients with BCECTS. METHODS: This case control study included 30 patients with BCECTS and 20 controls. Clinical assessment, neuropsychological tests, the Positive wave at 300 msec (P300) parameters recording, and quantitative electroencephalography (EEG) analysis were carried out for both groups. Alpha power ERD and ERS were measured in six different brain regions during an auditory oddball paradigm. RESULTS: Children with epilepsy showed a statistically significant poorer performance in verbal intelligence quotient (IQ), performance IQ, and total scale IQ and lower number of correct responses. Moreover, both groups showed diffuse alpha power attenuation in response to the target tones. After summation of the alpha power ERD over all brain regions to get the net diffuse ERD, the patients' group showed a statistically significant smaller net alpha ERD compared with that of the control group (P=0.001). No significant correlations between the alpha ERD percentage, recorded P300 parameters, and neuropsychological tests scores were found. CONCLUSIONS: Children with BCECTS have subtle cognitive dysfunction proved by significantly lower scores of verbal IQ and performance IQ subtests. The significantly smaller net diffuse alpha power ERD detected in children with epilepsy may be an electrophysiological indicator of disruptive brain activation in relation to cognitive attentional tasks; however, its correlation with neuropsychological tests was insignificant.


Assuntos
Atenção/fisiologia , Epilepsia Rolândica/fisiopatologia , Epilepsia Rolândica/psicologia , Testes Neuropsicológicos/estatística & dados numéricos , Desempenho Psicomotor/fisiologia , Adolescente , Encéfalo/fisiopatologia , Estudos de Casos e Controles , Criança , Sincronização Cortical , Eletroencefalografia/métodos , Sincronização de Fases em Eletroencefalografia , Feminino , Humanos , Masculino
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...