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Ultrasound Obstet Gynecol ; 43(5): 541-7, 2014 May.
Artigo em Inglês | MEDLINE | ID: mdl-24265180

RESUMO

OBJECTIVE: To investigate longitudinal changes in the uterine artery mean pulsatility index (UtA-PI) and mean arterial pressure (MAP) in women who develop pre-eclampsia (PE) and gestational hypertension (GH). METHODS: This was a prospective longitudinal study of singleton pregnancies identified by screening at 11 + 0 to 13 + 6 weeks' gestation as being at high risk for PE. Measurements of UtA-PI and MAP were taken every 4 weeks until delivery and were compared in women who developed preterm PE, requiring delivery before 37 weeks, term PE and GH with those in women who remained normotensive. RESULTS: In the normal outcome group, UtA-PI decreased with gestational age and MAP decreased between 12 and 24 weeks and then increased. In the preterm PE group, as compared to the normal group, UtA-PI and MAP were higher from early pregnancy onward and the difference for both increased with gestational age. In the term PE group, UtA-PI was significantly increased only from 33 weeks onward and MAP was increased from 12 weeks onward but the difference from normal did not increase with gestation. In GH, UtA-PI did not differ significantly from normal but MAP was higher from 12 weeks onward. CONCLUSION: The study describes temporal changes in UtA-PI and MAP in normal pregnancies and in women who develop PE and GH.


Assuntos
Hipertensão Induzida pela Gravidez/diagnóstico por imagem , Pré-Eclâmpsia/diagnóstico por imagem , Primeiro Trimestre da Gravidez , Ultrassonografia Doppler em Cores , Artéria Uterina/diagnóstico por imagem , Útero/diagnóstico por imagem , Adulto , Pressão Sanguínea , Feminino , Idade Gestacional , Humanos , Hipertensão Induzida pela Gravidez/sangue , Recém-Nascido , Estudos Longitudinais , Pré-Eclâmpsia/sangue , Gravidez , Estudos Prospectivos , Fluxo Pulsátil , Artéria Uterina/fisiopatologia , Útero/irrigação sanguínea
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