RESUMO
The number and species of helminth parasites from three gemsbok (Oryx gazella) were recorded, and their faecal nematode egg counts and the level of pasture contamination determined. Six nematode genera were recovered and four species identified, of which Trichostrongylus rugatus was the most prevalent. Other nematode species recovered were Cooperia sp., Agriostomum sp., Haemonchus contortus, Nematodirus spathiger and Ostertagia ostertagi. None of the worms were present in all animals studied, and no new host associations were found. Cysticerci were recovered from the mesenteries of one gemsbok and a further two unidentifiable helminths were recovered from the abomasum and the kidney fat layer of another antelope.
Assuntos
Antílopes/parasitologia , Helmintíase Animal/epidemiologia , Helmintos/classificação , Helmintos/isolamento & purificação , Filogenia , Animais , Animais Selvagens/parasitologia , Fezes/parasitologia , Feminino , Helmintíase Animal/parasitologia , Masculino , Contagem de Ovos de Parasitas/veterinária , Poaceae/parasitologia , Prevalência , África do Sul/epidemiologiaRESUMO
Single and dual radionuclide techniques have been described in localization of parathyroid adenomas. Although single radionuclide imaging with Tc-99m sestamibi has many advantages, it can fail to demonstrate a parathyroid adenoma, which, in the case presented, is well demonstrated with dual radionuclide imaging. The authors recommend dual tracer imaging when searching for parathyroid adenoma.
Assuntos
Adenoma/diagnóstico por imagem , Radioisótopos do Iodo , Neoplasias das Paratireoides/diagnóstico por imagem , Tecnécio Tc 99m Sestamibi , Feminino , Humanos , Pessoa de Meia-Idade , Cintilografia , Técnica de Subtração , Fatores de TempoRESUMO
The effect of Adriamycin on rat heart mitochondrial DNA was determined by initially labelling the DNA with [Me-14C]thymidine. Animals subsequently received intravenously either Adriamycin (10 mg/kg) or saline (1 ml/kg) (control group). Animals later received [Me-3H]thymidine and were killed at 6, 14, 24 and 36 h after this. The heart mitochondrial DNA was separated into the linear, non-supercoiled and supercoiled forms by ultracentrifugation on formamide/sucrose sedimentation gradients, and the amount of 14C and 3H incorporated into the various forms of the DNA was determined by scintillation counting. The data suggest that Adriamycin may cause breakage of the mitochondrial DNA helix, and that it slows the rate of mitochondrial DNA synthesis and the formation of complete DNA molecules. These experiments show that Adriamycin does interact with heart mitochondrial DNA, and may explain the cardiac dysfunction association with Adriamycin use.
