Effects of multiwalled carbon nanotubes received orally during 6 days on the gastrointestinal tract.

The effects of multiwalled carbon nanotubes on epitheliocytes of different compartments of the gastrointestinal tract and urothelium of different compartments of the renal nephron were studied in CBA mice. The nanotubes affected mouse gastrointestinal mucosa and renal urothelium. The cell reaction in the macula densa of the renal distal tubules and the immune system reaction to oral nanotubes were detected. A possible effect of nanotubes administered orally on the renal filtration function was hypothesized.