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Int J Food Sci Nutr ; 65(7): 862-7, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24846002

RESUMO

The objective of this study was to evaluate the effect of micronized insoluble fiber from starfruit bagasse as an ingredient of a functional food (FF) or as micronized insoluble fiber-rich fraction (IFRF) and its effects in vivo on lipids metabolism in a murine model. Experimental animals were divided in four isoproteic (15.8%) treatments differing on the fiber and cholesterol level used. The micronized IFRF particle size ranged from 37.5 to 149 µm. Treatments with added IFRF and those including the FF lowered serum triacylglycerols, total cholesterol (TC), high-density lipoproteins (HDL), and low-density lipoproteins (LDL) concentrations (IFRF: 14.2, 25.4, 55.06, and 12.18%, respectively; FF: 30.18, 39.47, 35.11, and 43.18%, respectively). IFRF produced the overall highest serum hypolipidemic effect and prevented the development of non-alcoholic fatty liver. Both the IFRF and the FF exhibited hypolipidemic effects that suggest a potential role of starfruit insoluble fiber as a component of FFs aimed against cardiovascular diseases.


Assuntos
Averrhoa/química , Fibras na Dieta/farmacologia , Metabolismo dos Lipídeos/efeitos dos fármacos , Ração Animal , Animais , Dieta/veterinária , Fibras na Dieta/análise , Frutas/química , Camundongos , Tamanho da Partícula
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