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1.
Cureus ; 14(2): e22692, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-35386164

RESUMO

Gastric ischemia is a condition of hypo-perfusion associated with hypotension, vasculitis, and thromboembolism. We report a case of a gastric outflow obstruction due to sizeable visceral artery thrombo-embolism leading to the ischemic conclusion, the frailty, multiple comorbidities deeming general anesthesia (GA) risky, and the patient's decision not to have an open surgery under GA. Invasive procedures in patients with similar profiles like our patient are usually not risk-free, this leads the intervention radiology team to believe a minimally invasive procedure while avoiding GA might be optimal. A 63-year-old female with multiple comorbidities came eight weeks after significant surgery complaining of severe acute epigastric pain, abdominal distention and rigidity, and persistent vomiting. Further investigations showed obstruction in the gastric antrum and pyloric canal. Three separate endoscopic attempts to find and cross the stricture failed. Firstly, gastrostomy access was established, but due to the stomach being massively distended, passing a guidewire through the pylorus failed despite using multiple hydrophilic wires and pre-shaped catheters, this is due to the collapsed pylorus. Subsequently, two attempts under ultrasound guidance to puncture the duodenal bulb and pass a wire and catheter through the antrum stricture were unsuccessful, and another attempt was considered of high risk. An alternative approach through the gallbladder was established, and cholangiography was performed to delineate the anatomy. Then an approach through the right hepatic duct and ampulla of Vater was successfully performed. The attempted passage through the stricture was successful. The dilation was successful, and the patient tolerated both fluid and solids orally. Due to having such a frail patient, interventions of minimal invasiveness and favorable outcome are welcomed. This case report suggests that this technique showed satisfactory results and achieved the goal to improve the overall quality of life where the patient had a good oral intake with no post-operation complications.

2.
Cureus ; 14(12): e32702, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-36686145

RESUMO

Background Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by defective social communication and interaction with a repetitive pattern of monotonous or stereotyped behavior. Although the exact etiology of ASD is unknown, many factors may be implicated in the development of ASD. We aimed to determine the correlation between specific parental factors and Autism Treatment Evaluation Checklist (ATEC) scores. Methods This cross-sectional study was conducted at the Prince Nasser Bin Abdulaziz Center for Autism, Autism Center for Excellence, and Academy of Special Education for Autism in Riyadh, Saudi Arabia. We enrolled children diagnosed with ASD and their parents from these centers. Data were collected through self-administered questionnaires to the patients' parents. Results All included children were <18 years old. In total, 71 (92.2%) children were male and six (7.8%) were female. Further, 77 (100%) patients were diagnosed with autistic disorder. Children of consanguineous parents, underweight mothers and obese fathers, mothers with a history of depression during pregnancy, and mothers aged ≥31 years during pregnancy tend to have a higher mean ATEC score. The health domain was the most significantly correlated with ATEC scores, with a Pearson correlation of 0.880. In linear regression analysis, only maternal depression during pregnancy was significantly correlated with ATEC scores. Conclusion Our patients had a mean ATEC score of 86.2. The health domain was the most significantly correlated with ATEC scores, with a Pearson correlation of 0.880. Linear regression analysis revealed that consanguinity, parental chronic disease, parental allergy, smoking, drug use during pregnancy, paternal and maternal body mass index (BMI), and sibling number were not significantly correlated with ATEC scores (P=0.701, 0.693, 0.133, 0.874, 0.982, 0.255, 0.778, and 0.502, respectively). However, maternal depression during pregnancy was significantly correlated with ATEC scores (P=0.055).

3.
Cureus ; 13(12): e20540, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34950561

RESUMO

Introduction Mental well-being is an essential aspect of general health. Assessing mental well-being is crucial to leading a healthy life. The global population is, presumptively, affected at a ratio of one out of four individuals with a mental or neurological disorder. This further emphasized the importance of the financial, social, and health implications that ensue. Methods and materials Data collection was performed using the symptoms checklist-90 (SCL-90) survey between March and April of 2021. The data collected included demographic data as well as nine domains that include some of the most common psychiatric symptoms. The collected questionnaires were analyzed using the Kolmogorov-Smirnov and Shapiro-Wilk tests. Non-parametric tests were utilized, as the SCL-90 dimensions and global index scores follow a non-normal distribution. Results The questionnaire yielded 387 responses. Females comprised the majority of the participants. The most prevalent symptom described as extremely common by females was waking up early in the morning. The most commonly described symptom described as not at all by females was hearing words that others do not hear. There was no statistical difference in mental well-being between males and females. Older participants (>40 years old) had better mental well-being in comparison to their younger counterparts. Conclusion During the fallout of the coronavirus disease 2019 (COVID-19) pandemic, much attention and resources were allocated toward the physical aspect of the pandemic, yet the psychological implications must not be understated. Multiple variables, such as age, marital status, and unemployment, may impact the mental well-being of the population and must be further assessed.

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