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1.
Medicine (Baltimore) ; 94(10): e634, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25761194

RESUMO

Local complications at the radial access site are not frequent, hence its large diffusion as the preferred access route for endovascular procedures. However, in a time of fast widespreading, better comprehension of all potential complications becomes critical to facilitate their early recognition and the most appropriate treatment. In this case report, we present for the first time a case of sudden massive bleeding at the left wrist, due to spontaneous gross rupture of the left radial artery bleeding 15 days after an endovascular procedure through a left radial arterial access. The patient had been readmitted to the hospital after evidence of local infection at the left wrist with loss of substance. The radial artery was patent with no evidence of pseudoaneurysm. After sudden radial artery rupture, with massive bleeding and suspicion that the local infection could have reached the arterial wall, surgical hemostasis with artery ligation was obtained. Healing of the large wound was then efficiently speeded up using a negative pressure wound therapy. This is the first case of macroscopic radial artery rupture associated with local wrist infection after arterial catheterization. After prompt surgical hemostasis, negative pressure wound therapy was very helpful in favoring healing of the large and deep wound.


Assuntos
Cateterismo Cardíaco/métodos , Cateterismo Periférico/efeitos adversos , Angiografia Coronária/efeitos adversos , Hemorragia/etiologia , Artéria Radial/lesões , Idoso , Angiografia Coronária/métodos , Hemorragia/cirurgia , Hemostasia Cirúrgica/métodos , Humanos , Masculino , Tratamento de Ferimentos com Pressão Negativa , Intervenção Coronária Percutânea , Ruptura Espontânea , Infecção da Ferida Cirúrgica/terapia , Fatores de Tempo , Grau de Desobstrução Vascular
2.
Nutr Metab Cardiovasc Dis ; 15(5): 368-72, 2005 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-16216723

RESUMO

BACKGROUND AND AIM: The metabolic syndrome is a highly prevalent condition associated with cardiovascular disease. However, the contribution of LDL to cardiovascular risk is not estimated since it is not part of ATP III criteria. METHODS AND RESULTS: This is an observational study evaluating the association between metabolic syndrome and carotid atherosclerosis, according to LDL cholesterol levels. Two hundred and sixty-five menopausal women were consecutively enrolled, they all underwent clinical examination, biochemical characterization and ultrasound evaluation. In particular, carotid atherosclerosis, a well known marker of cardiovascular disease, was evaluated. Women affected by cardiovascular disease were excluded from the study. The metabolic syndrome was found strongly associated with carotid atherosclerosis in our study population. In individuals with normal or near normal LDL, the incidence of carotid atherosclerosis was significantly lower than in subject with high LDL. A high plasma LDL concentration was independently associated with carotid atherosclerosis (p=0.026) among women with the metabolic syndrome. CONCLUSIONS: High LDL cholesterol levels are associated with carotid atherosclerosis in menopausal women with the metabolic syndrome. Although it remains prudent to recommend an integrated control of all modifiable risk factors to prevent cardiovascular disease, decreasing LDL levels should be considered a high priority.


Assuntos
Doenças das Artérias Carótidas/sangue , Doenças das Artérias Carótidas/complicações , LDL-Colesterol/sangue , Menopausa , Síndrome Metabólica/complicações , Idoso , Glicemia/análise , Pressão Sanguínea , Doenças das Artérias Carótidas/diagnóstico por imagem , HDL-Colesterol/sangue , Feminino , Humanos , Síndrome Metabólica/fisiopatologia , Pessoa de Meia-Idade , Razão de Chances , Fatores de Risco , Triglicerídeos/sangue , Ultrassonografia
3.
Am J Cardiol ; 94(2): 266-9, 2004 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-15246921

RESUMO

Due to the lack of convincing data about the association between atherosclerosis and osteoporosis, we evaluated the association between carotid atherosclerosis and bone mineral density in a sample of apparently healthy postmenopausal women who underwent health-screening in our hospital. We also evaluated a bone turnover marker, osteocalcin; we divided the population into 2 groups according to osteocalcin levels. We found a high prevalence of carotid atherosclerosis in subjects with high osteocalcin levels and low bone mineral density.


Assuntos
Densidade Óssea , Doenças das Artérias Carótidas/fisiopatologia , Doenças das Artérias Carótidas/epidemiologia , Comorbidade , Feminino , Humanos , Modelos Logísticos , Pessoa de Meia-Idade , Osteocalcina/sangue , Osteoporose Pós-Menopausa/epidemiologia , Pós-Menopausa , Fatores de Risco
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