RESUMO
In immunocompetent patients, paranasal invasive aspergillosis is rare and has a high recurrence rate. Twenty-three cases of paranasal invasive aspergillosis, involving 14 male and nine female immunocompetent patients were reviewed. All patients were cancer-free, HIV-negative, with normal WBC, and none of the patients had received immunosuppressive therapy or corticosteroids. Mean duration of symptoms before diagnosis was 18 months. Aspergillus flavus was the species most frequently isolated. Surgical debridement was performed in all patients followed by antifungal therapy in 18 patients. Mean follow-up duration was 30 months. Fourteen patients relapsed after a mean of 13 months and required an average of 4.3 admissions for repeat surgical evacuation. In a logistic regression model, relapse was not associated with age, duration of symptoms, clinical findings, extent of disease, or mode of therapy. However, patients who were relapse-free tended to have had complete surgical evacuation followed by antifungal therapy.
Assuntos
Aspergilose/cirurgia , Aspergillus flavus/crescimento & desenvolvimento , Doenças dos Seios Paranasais/microbiologia , Adolescente , Adulto , Antifúngicos/uso terapêutico , Aspergilose/tratamento farmacológico , Criança , Desbridamento , Feminino , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Doenças dos Seios Paranasais/tratamento farmacológico , Doenças dos Seios Paranasais/cirurgia , Recidiva , Estudos Retrospectivos , Fatores de Risco , Arábia SauditaAssuntos
Infecções Oportunistas Relacionadas com a AIDS/microbiologia , Abscesso Abdominal/microbiologia , Apendicite/microbiologia , Infecções por Mycobacterium não Tuberculosas/microbiologia , Mycobacterium kansasii , Infecções Oportunistas Relacionadas com a AIDS/tratamento farmacológico , Abscesso Abdominal/complicações , Abscesso Abdominal/tratamento farmacológico , Apendicite/complicações , Apendicite/tratamento farmacológico , Criança , Humanos , Masculino , Infecções por Mycobacterium não Tuberculosas/complicações , Infecções por Mycobacterium não Tuberculosas/tratamento farmacológicoRESUMO
An unusual case of granulocytic sarcoma developing at the site of a previous cerebral hemorrhage in a patient with acute myelogenous leukemia in complete hematological remission is presented. The pathogenesis of the tumor growth at this site and its relevance to the antecedent hemorrhage are discussed.
