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1.
Eur J Pediatr Surg ; 16(6): 415-9, 2006 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-17211790

RESUMO

PURPOSE: Nonparasitic splenic cysts (NPSCs) are uncommon in children. The aim of this multinational and multicentric study was to present the authors' experience as well as the changing trends in the management of NPSCs over the last 25 years. MATERIAL AND METHODS: From 1981 to 2005, 50 children or adolescents were surgically treated for NPSCs in 6 paediatric surgical centres in four European countries. The medical records of these 50 patients with NPSCs were reviewed retrospectively. RESULTS: Twenty-six male and 24 female patients were operated on. Age at surgery ranged from 1 to 17 years (mean 11.9). Seventeen patients were symptomatic. Six total (4 open and 2 laparoscopic) and 26 partial (22 open and 4 laparoscopic) splenectomies were performed. Laparoscopic fenestration or deroofing and open cystectomy was carried out in 9 patients, respectively. Histological findings revealed the lesion to be an epidermoid cyst (n = 28), a pseudocyst (n = 15) or a mesothelial cyst (n = 2). In 5 patients haemangioma or lymphangioma was the pathological diagnosis. At a mean follow-up of 2.9 years, residual cysts were found in 8 laparoscopically treated patients, 4 of whom required re-do laparoscopy or open surgery. CONCLUSIONS: Over the last two decades, the surgical treatment of NPSCs has changed from a formerly customary total splenectomy to spleen-conserving procedures, such as total cystectomy with or without partial splenectomy or partial cystectomy. These therapeutic modalities can be performed laparoscopically, if technically possible. Fenestration or deroofing of the cyst resulted in a high recurrence rate (7/9).


Assuntos
Cistos/cirurgia , Esplenopatias/cirurgia , Adolescente , Criança , Pré-Escolar , Cistos/diagnóstico , Feminino , Humanos , Achados Incidentais , Lactente , Masculino , Estudos Retrospectivos , Esplenopatias/diagnóstico
4.
Biull Eksp Biol Med ; 101(6): 712-4, 1986 Jun.
Artigo em Russo | MEDLINE | ID: mdl-3460643

RESUMO

A comparative analysis of the effect of racemic PGF2 alpha--(+/-)PGF2 alpha, 15 alpha OH-II-deoxy-PGE1-(+/-)DPGE1, aceclidine, neostigmine methylsufate, galanthamini hydrobromidum, and pituitrine on the ileum motility was performed in rabbits with dynamic ileus induced by surgical trauma and peritonitis. In the model under study (+/-)PGF2 alpha was similar in its action to neostigmine methylsulfate and aceclidine, with (+/-)DPGE1 having a week effect.


Assuntos
Alprostadil/análogos & derivados , Motilidade Gastrointestinal/efeitos dos fármacos , Obstrução Intestinal/fisiopatologia , Intestino Delgado/fisiopatologia , Prostaglandinas F/farmacologia , Alprostadil/farmacologia , Animais , Dinoprosta , Obstrução Intestinal/etiologia , Masculino , Peritonite/complicações , Prostaglandinas E Sintéticas/farmacologia , Prostaglandinas F Sintéticas/farmacologia , Coelhos , Estereoisomerismo
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