RESUMO
Cross sectional surveys have shown an increasing prevalence of Helicobacter pylori (H pylori) infection with increasing age in Western populations. The aim of this study was to examine the pattern of acquisition of H pylori infection over a 21 year period in a group of 141 adults who had blood samples and serum stored in 1969, 1978, and 1990. A prevalence of H pylori antibody of 39% in 1969 serum samples, 40.9% in 1978, and 34.8% in 1990 was found when assessed by an enzyme linked immunosorbent assay (ELISA). Of the 86 subjects who were seronegative in 1969, only six (7%) were seropositive in 1990. These data suggest that a cohort effect may contribute to the pattern of increasing prevalence of H pylori infection seen with increasing age. Acquisition of infection in adults is rare. It is unlikely, therefore, that reinfection will occur after successful eradication.
Assuntos
Infecções por Helicobacter/etiologia , Helicobacter pylori , Adulto , Fatores Etários , Idoso , Anticorpos Antibacterianos/análise , Estudos de Coortes , Feminino , Infecções por Helicobacter/epidemiologia , Infecções por Helicobacter/imunologia , Helicobacter pylori/imunologia , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Austrália Ocidental/epidemiologiaRESUMO
Chlorhexidine/EDTA/Tris was more active compared with chlorhexidine against the following species of organisms: Acinetobacter species, Citrobacter species, Enterobacter species, Escherichia coli, Proteus mirabilis, Providence species, Pseudomonas species, Staphylococcus aureus, Staphylococcus epidermidis and Streptococcus faecalis, when tested in isosensitest agar. The addition of 20% serum to the medium reduced its effectiveness mainly against Providence species, Proteus species, and Streptococcus faecalis. However, the potential for this solution as a bladder instillation or topical antiseptic should be considered because of its reduced side effects compared with chlorhexidine alone, and its increased general effectiveness against all isolates tested.