RESUMO
In a recent article, Eastwick, Finkel, Mochon, and Ariely (2007) reported data to indicate that selectivity might be an important factor in determining romantic desire. Using a speed-dating paradigm, they found that individuals who, on average, rated potential dates as highly desirable were likely to receive lower average ratings from their dates, as evidenced by what they termed as negative generalized correlations. However, the dyadic correlations were positive, suggesting that, across pairs, desire was somewhat reciprocated. Eastwick et al. go as far as to claim that "... daters somehow broadcast their unselec-tivity... " (page 318), which we find to be a deeply dissatisfying explanation. We present an alternative and more principled approach in order to account for the disassociation between the generalized and dyadic correlations. We implemented a multi-agent model that allows an assessment of the relative contributions of selectivity and matching on ratings of attractiveness. The model suggests that the match between potential daters' attractiveness is the most important predictor of romantic desire. We believe that Eastwick et al's (2007) article is just another example of a dangerous pattern in social psychology research: spectacular claims are made on the flimsiest of evidence.
En un artículo reciente, Eastwick, Finkel, Mochon y Ariely (2007) reportaron datos que indicaban que la selectividad podría ser un factor importante para determinar el deseo romántico. Usando un paradigma de citas rápidas, se encontró que los individuos que en promedio calificaron posibles citas como altamente deseables eran los que recibían más bajas calificaciones en promedio de sus citas, como lo que demuestra lo que ellos denominan como correlaciones negativas generalizadas. Sin embargo, las correlaciones diádicas fueron positivas, lo que sugiere que, a través de pares el deseo era algo recíproco. Eastwick et al. (2007) van más lejos al afirmar que " ... personas que se citan de alguna manera difunden su no selectividad... " (p 318), donde encontramos una explicación profundamente desalentadora. Presentamos una aproximación alternativa y un enfoque basado en la disociación entre las correlaciones generalizadas y diádicas. Hemos implementado un modelo multi-agente que permite una evaluación de las contribuciones relativas de la selectividad y la congruencia en las calificaciones de la atracción. El modelo sugiere que la igualación entre el atractivo potencial de personas que se citan es el predictor más importante del deseo romántico. Creemos que el artículo de Eastwick et al (2007) es sólo otro ejemplo de un patrón peligroso en la investigación en el campo de la psicología social: las afirmaciones espectaculares son realizadas con la evidencia más débil.
Assuntos
Cognição , Relações InterpessoaisRESUMO
Tissue neovascularization involves recruitment of circulating endothelial progenitor cells that originate in the bone marrow. Here, we show that a class of embryonic endothelial progenitor cells (Tie-2+, c-Kit+, Sca-1+, and Flk-1-/low), which were isolated at E7.5 of mouse development at the onset of vasculogenesis, retain their ability to contribute to tumor angiogenesis in the adult. Using intravital fluorescence videomicroscopy, we further defined the multistep process of embryonic endothelial progenitor cell (eEPC) homing and incorporation. Circulating eEPCs are specifically arrested in "hot spots" within the tumor microvasculature, extravasate into the interstitium, form multicellular clusters, and incorporate into functional vascular networks. Expression analysis and in vivo blocking experiments provide evidence that the initial cell arrest of eEPC homing is mediated by E- and P-selectin and P-selectin glycoprotein ligand 1. This paper provides the first in vivo insights into the mechanisms of endothelial progenitor cell recruitment and, thus, indicates novel ways to interfere with pathological neovascularization.
