Prospective comparison of 3 dacryocystorhinostomy surgeries: external versus endoscopic versus transcanalicular multidiode laser.

PURPOSE: To analyze the clinical outcomes of external (EX-), endoscopic (EN-), and transcanalicular multidiode laser (TC-) with dacryocystorhinostomy (DCR). METHODS: Ninety-two patients with primary acquired nasolacrimal duct obstruction were enrolled (divided into EX-DCR [n = 33], EN-DCR [n = 30], and TC-DCR groups [n = 29]) in this prospective study. Primary outcome measures were the anatomical and functional success of operations at the last control examination. Secondary outcome measures were the ostium size, surgical time, and complications. RESULTS: The difference in mean surgical time among the 3 groups was statistically significant (p < 0.0001). External DCR required the longest surgical time (46.6 ± 15.3 minutes), while TC-DCR was the shortest (20.3 ± 7.7 minutes). There were no significant differences between the groups regarding anatomical (81.8%, 75.9%, and 76.7% in EX-, EN-, and TC-DCR groups, respectively; p = 0.824) and functional success rates (81.8%, 72.4%, and 73.3% in EX-, EN-, and TC-DCR groups, respectively; p = 0.626). Final ostium size was the largest with EX-DCR (33.7 ± 17.4 mm) and smallest with EN-DCR (19.0 ± 8.9 mm; p = 0.001). The complication rate was similar in all groups. The most common complications were the formation of granulation tissue (16.3%) and intranasal synechiae (9.8%), all of which led to surgical failure and were more frequent in the EN- and TC-DCR groups. CONCLUSIONS: External DCR, EN-DCR, and TC-DCR had similar success and complication rates in patients with primary acquired nasolacrimal duct obstruction. External DCR resulted in the largest ostium size. Transcanalicular DCR appeared to be effective with the shortest surgical time.

Irrational use of antibiotics among university students.

STUDY OBJECTIVE: The aim of the presented study was to evaluate the knowledge, attitude and behaviour of antibiotic usage in the student groups of a University in a country where the antibiotics are taken without prescriptions. DESIGN: Out of 5345 students (excluding those from the Faculty of Medicine) of Ege University, 678 were chosen by systematic sampling methods. The sampling group was divided into two groups. Group A included students from the Faculties of Pharmacy and Dentistry and Group B was composed of students of all other faculties. A questionnaire was used. MAIN RESULTS: The mean age was 21.0+/-3.0 and 58% were females. The aim of antibiotic use for common cold was 83.1% (P>0.05) and, to decrease fever was 32.1% (P<0.05) in both Groups. In Group A 36.1% and in Group B 44.9% of the respondents started antibiotics by themselves when they were ill (P>0.05) although 89.1% of both groups agree that antibiotics should be started with doctors' prescription. During their last infection in Group A 11.7% and in Group B 27.3% of the respondents used the same antibiotic as previously prescribed by their doctors and the use of antibiotics as advised by the doctors during their last infection was 50.8% in Group A and 35.3% in Group B. CONCLUSIONS: The use of antibiotics are found to be irrational among university students. National education programmes about the dangers of irrational antibiotic use and restriction of antibiotics without prescriptions should be the priority. This study indicated that knowledge regarding antibiotics cannot be evaluated alone since it did not always correlate with behaviour.

Rational antibiotic use and academic staff.

This study was devised to determine the knowledge, attitude and behaviour of an educated group of people towards antibiotic use and self-medication with antibiotics. Of 1380 members of academic staff (excluding those from the Faculty of Medicine) of Ege University, 602 were chosen by systematic sampling methods. Two groups were formed. Group A included academic staff from the Faculties of Dentistry and Pharmacy and Group B, members of all other faculties. The mean age was 37.4+/-11.0 and 47.0% were females. The mean antibiotic knowledge score was 7.16+/-3.32. Self-medication with antibiotics was admitted by 45.8% of the total samle and 15.6% of the respondents used antibiotics until their symptoms disappeared regardless of the period of prescription. In Group A 48.8% and in Group B 80.7% of the respondents believed that antibiotics could be used for common cold. It is concluded that priority should be given to knowledge-based behaviour education programmes for the more highly educated community; there must also be restriction on the sale of antibiotics without prescription.