[The AGAT-R2, a gamma therapeutic apparatus with programmed control]. / Gamma-terapevticheskii apparat s programmnym upravleniem AGAT-R2.

The paper is concerned with analysis of a new programmed-control gamma-therapeutic apparatus AGAT-P2 for gamma-beam therapy of cancer patients.

[Survival of clonogenic cells of Lewis lung carcinoma cells forming colonies in agar cultures in diffusion chambers during gamma-irradiation and exposure to gamma-neutron californium-252 irradiation]. / Vyzhivaemost' klonogennykh kletok karsinomy legkikh L'iuis, formiruiushchikh kolonii v agarovykh kul'turakh v diffuzionnykh kamerakh, pri gamma-obluchenii i vozdeistvii gamma-neitronnogo izlucheniia kaliforniia-252.

Clonogenic cells forming colonies in agar cultures in diffusion chambers and those isolated from subcutaneously transplanted Lewis lung carcinoma do not differ in their sensitivity to 60Co gamma-rays with respect to tumor growth stages. The dose-survival curves for all studied cells are S-shaped with a small shoulder. A cumulative dose-survival curve for malignant clonogenic cells is characterized by the average value of mean lethal dose D0 = 2.24 Gy and extrapolation number n = 2.0. When exposed to gamma-neutron-radiation (252Cf) malignant clonogenic cells exhibit a nearly exponential dose-survival curve with D0 = 0.56 Gy (with respect to a neutron component). The RBE of gamma-neutron radiation (252Cf) is 2.5.