[Immunomorphological identification of an antigen associated with squamous cell carcinoma of the cervix uteri]. / Immunomorfologicheskaia identifikatsiia antigena, assotsiirovannogo s ploskokletochnym rakom sheiki matki.

Data on immunomorphological identification of antigen associated with cervical squamous cell carcinoma are presented. Tissue specimens prepared of cervical squamous cell carcinoma, normal cervical tissue and different other human tumours have been stained immunohistochemically for antigen using a polyclonal antiserum. Immunofluorescence staining for tumour-associated antigen was observed in all specimens of cervical squamous cell carcinoma and in 20% of specimens of the normal cervix uteri. The above antigen is a high specific tumour-associated marker and may be useful in the diagnostic studies.

[A tumor-associated antigen of cervical cancer]. / Opukholeassotsiirovannyi antigen raka sheiki matki.

The tumour-associated antigen was identified with the aid of antisera obtained from rabbits immunized with 3 M KCl extract of pool human cervical carcinoma cells. The antigen was found in 92.5% specimens of human cervical squamous cell carcinoma, in 4.7% specimens of other localization of the tumours. The antigen was absent from sets of normal human tissues. The tumour-associated antigen was not identical with CEA, alpha-fetoprotein, SP1, EPA and lactoferrin and it was localized in cytoplasm of cervical carcinoma cells.