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1.
World Neurosurg ; 95: 464-468, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-27544339

RESUMO

BACKGROUND: The collection of the greatest possible amount of pathologic tissue is of paramount importance in neurosurgery to achieve the most accurate histopathologic diagnosis, to perform all of the necessary biomolecular tests on the pathologic specimen, and to collect biological material for basic or translational science studies. This problem is particularly relevant in pituitary surgery because of the possible small size and soft consistency of tumors, which make them suitable for removal through suction, reducing the amount of available pathologic tissue. To solve this issue, we adopted a filter connected to the suction tube, which allows the surgeon to collect all of the tissue aspirated during surgery. METHODS: Our experience of 1734 endoscopic endonasal procedures, performed adopting this device since 1998 to December 2015, has been revised to assess its advantages and limitations. RESULTS: This system is easy-to-use, does not impair the surgical maneuvers, and does not add any relevant cost to the surgery. The tissue collected through the filter proved useful for diagnostic histologic and biomolecular analyses and for research purposes, without any relevant artifacts as a result of this method of collection. CONCLUSIONS: The use of a filter has allowed us to obtain the greatest amount possible of pathologic tissue at each surgery. This surgical material has revealed to be helpful both for diagnostic and basic science purposes. The use of the filter has proven to be of particular importance for microadenomas, soft tumors, and supradiaphragmatic or skull base lesions with heterogeneous features, improving the accuracy of histopathologic diagnosis.


Assuntos
Neoplasias do Sistema Nervoso Central/cirurgia , Neuroendoscopia/instrumentação , Sucção/instrumentação , Adenoma/cirurgia , Cistos do Sistema Nervoso Central/cirurgia , Condrossarcoma/cirurgia , Cordoma/cirurgia , Fossa Craniana Posterior/cirurgia , Craniofaringioma/cirurgia , Glioma/cirurgia , Humanos , Neoplasias Hipotalâmicas/cirurgia , Neoplasias Meníngeas/cirurgia , Meningioma/cirurgia , Cirurgia Endoscópica por Orifício Natural , Neuroendoscopia/métodos , Nariz , Neoplasias Hipofisárias/cirurgia , Plasmocitoma/cirurgia , Estudos Retrospectivos , Neoplasias da Base do Crânio/cirurgia , Sucção/métodos
2.
Artigo em Inglês | WPRIM (Pacífico Ocidental) | ID: wpr-32546

RESUMO

OBJECTIVES: Epistaxis is one of the most common otorhinolaryngologic emergencies representing more than 12% of conditions managed at the Ear, Nose and Throat (ENT) Emergency Consulting Room of our Otorhinolaryngologic Unit each year. The elevated frequency of this pathology makes it necessary to adopt the most effective and least expensive therapeutic strategy available. The aim of this study was to compare the efficacy, costs and morbidity of nasal packing (NP), which is the mainstay of treatment for anterior epistaxis in our ENT Emergency Consulting Room versus submucosal infiltrations of lauromacrogol (LA). METHODS: A retrospective study was designed from August 2012 to April 2013 involving 53 patients suffering from anterior epistaxis. Anterior NP was used in 27 patients versus 26 patients undergoing 27 procedures performed with submucosal infiltrations of LA (or polidocanol). Outcomes for each treatment were evaluated. Patients in group 1 were treated with LA 400 injection next to the bleeding point: 0.5- to 1-mL single or multiple infiltrations with a 27-gauge needle. The whitening of the nasal mucosa around the bleeding point during infiltration was considered a marker of correct procedure in order to achieve the best results. Bilateral treatment was also performed at the same time. Patients in group 2 were treated with standard NP. RESULTS: Bleeding recurrence was higher in the NP group even if it was not statistically significant (P=0.2935). However, the LA infiltrations were better tolerated with lower morbidity and costs as compared to NP. No complications were observed in either group. CONCLUSION: LA infiltrations were shown to be a viable alternative in anterior epistaxis treatment. They are safe, easy to use with good efficacy and have a low cost.


Assuntos
Humanos , Orelha , Emergências , Epistaxe , Hemorragia , Mucosa Nasal , Agulhas , Nariz , Patologia , Faringe , Polietilenoglicóis , Recidiva , Estudos Retrospectivos , Escleroterapia
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