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1.
Clin Neurol Neurosurg ; 210: 107011, 2021 11.
Artigo em Inglês | MEDLINE | ID: mdl-34741975

RESUMO

Cerebral Proliferative Angiopathy (CPA) is a rare vascular malformation that is distinguished from classical brain arteriovenous malformations (AVM) in its imaging findings and clinical progression but more importantly in its pathophysiology. Here we report the case of a 37-year-old male patient with CPA accompanied by Cerebral Cavernous Malformation (CCM) in hopes to expand the inquiry into the pathophysiology of this rare lesion. A patient with progressive headache, right-sided weakness, and impaired speech were evaluated at our medical center. Neuroimaging studies were performed, and the patient was diagnosed with CPA. The patient has been followed up with conservative management and periodic neuroradiological evaluation for 5 years. Digital subtraction angiography (DSA) showed a vascular malformation diffusely covering the left hemisphere that is consistent with CPA. In addition, 2 sequential CCMs were detected in the right hemisphere. Also, the patients' familial history included two brothers with CCMs. The coexistence of CPA with CCM and patients' familial history of CCM could suggest the possibility of a common pathophysiological element.


Assuntos
Doenças de Pequenos Vasos Cerebrais/complicações , Doenças de Pequenos Vasos Cerebrais/diagnóstico por imagem , Hemangioma Cavernoso do Sistema Nervoso Central/complicações , Hemangioma Cavernoso do Sistema Nervoso Central/diagnóstico por imagem , Adulto , Anticonvulsivantes/uso terapêutico , Antipsicóticos/uso terapêutico , Doenças de Pequenos Vasos Cerebrais/tratamento farmacológico , Gabapentina/uso terapêutico , Haloperidol/uso terapêutico , Hemangioma Cavernoso do Sistema Nervoso Central/tratamento farmacológico , Humanos , Masculino
2.
Infez Med ; 27(1): 85-92, 2019 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-30882385

RESUMO

Invasive aspergillosis is a severe infection that generally involves the lungs. Primary gastrointestinal aspergillosis is the least common form of invasive aspergillosis. A patient aged 65 years developed a febrile neutropenic episode following an autologous stem cell transplant for plasmacytoid variant diffuse large B-cell gastric non-Hodgkin's lymphoma. He had abdominal pain on the second day of the febrile neutropenic episode and ileus occurred on the sixth day. His general condition deteriorated despite broad spectrum antibiotics and caspofungin treatment, and intestinal perforation occurred on the nineteenth day of the febrile neutropenic episode. Pathological examination of the resected jejunum and ileum revealed mould hyphae compatible with aspergillus. The patient died due to massive gastrointestinal bleeding on the fifth post-operative day. Although a rare condition, primary gastrointestinal aspergillosis should be kept in mind while treating neutropenic patients with gastrointestinal symptoms.


Assuntos
Aspergilose/complicações , Neutropenia Febril/microbiologia , Gastroenteropatias/microbiologia , Transplante de Células-Tronco Hematopoéticas , Infecções Fúngicas Invasivas/microbiologia , Idoso , Protocolos de Quimioterapia Combinada Antineoplásica/efeitos adversos , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Aspergilose/diagnóstico por imagem , Evolução Fatal , Gastroenteropatias/diagnóstico por imagem , Humanos , Íleus/etiologia , Hospedeiro Imunocomprometido , Infecções Fúngicas Invasivas/diagnóstico por imagem , Linfoma Difuso de Grandes Células B/terapia , Masculino , Neoplasias Gástricas/terapia
3.
Euroasian J Hepatogastroenterol ; 7(2): 178-180, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29201804

RESUMO

AIM: A case of asymptomatic aneurysm of spontaneous portosystemic venous fistula (SPVF) with the radiologic findings is described. BACKGROUND: Although advances and more widespread use of ultrasound (US) and computed tomog -raphy angiography (CTA) have enabled more detection of SPVF in the liver, it is a rare entity. CASE REPORT: A 49-year-old male was referred to our hospital's nephrology outpatient clinic due to hypertension. Abdominal sonography examination detected a well-defined cystic lesion adjacent to the middle hepatic vein in the liver. The lesion showed venous flow in the color Doppler US examination. Computed tomography angiography examination revealed an aneurysm of the fistula. CONCLUSION: Radiologists should be aware of this vascular anomaly and cyst-like lesions in the liver should be examined with color Doppler ultrasonography for possible vascularization, and be differentiated with CTA if necessary. CLINICAL SIGNIFICANCE: This condition is usually encountered incidentally and patients usually have no symptoms. However, severe complications, such as hepatopulmonary syndrome, liver tumors, encephalopathy, and heart failure can be seen.How to cite this article: Ulus S, Akan GE, Erol C. Aneurysm of Portosystemic Fistula: A Case Report and Review of Literature. Euroasian J Hepato-Gastroenterol 2017;7(2):178-180.

4.
Spine J ; 16(10): e671-e672, 2016 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-26968239
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