Development of NIRS probe based on LED sensing that enables multimodal integration.

We propose LED sensing which provides the miniaturization and symmetrization for NIRS sensor system. In order to make it into practical application, the spectral responses of LEDs were investigated and then formula for calculating changes in hemoglobin concentrations were established. In blood phantom experiment, temporal changes in hemoglobin concentration were observed by CW-NIRS using LED sensing.