Design of malaria diagnostic criteria for the Sysmex XE-2100 hematology analyzer.

Thick film, the standard diagnostic procedure for malaria, is not always ordered promptly. A failsafe diagnostic strategy using an XE-2100 analyzer is proposed, and for this strategy, malaria diagnostic models for the XE-2100 were developed and tested for accuracy. Two hundred eighty-one samples were distributed into Plasmodium vivax, P. falciparum, and acute febrile syndrome groups for model construction. Model validation was performed using 60% of malaria cases and a composite control group of samples from AFS and healthy participants from endemic and non-endemic regions. For P. vivax, two observer-dependent models (accuracy = 95.3-96.9%), one non-observer-dependent model using built-in variables (accuracy = 94.7%), and one non-observer-dependent model using new and built-in variables (accuracy = 96.8%) were developed. For P. falciparum, two non-observer-dependent models (accuracies = 85% and 89%) were developed. These models could be used by health personnel or be integrated as a malaria alarm for the XE-2100 to prompt early malaria microscopic diagnosis.

Helicobacter pylori y plaquetas: informe preliminar: [revisión] / Helicobacter pylori and platelets: preliminary report: [review]

De acuerdo con la literatura científica, la infección por Helicobacter pylori (H. pylori) es un problema creciente de salud pública en países en vía de desarrollo, como Colombia, con graves repercusiones gastrointestinales y extradigestivas, como son las alteraciones hematológicas, principalmente asociadas con las plaquetas, que pueden aumentar el riesgo cardiovascular, en particular el recuento de plaquetas y el porcentaje de plaquetas inmaduras. Objetivo: determinar la relación entre la infección por H. pylori y la presencia de alteraciones plaquetarias en una población sana de individuos...