RESUMO
Since March 2020, the world is involved in the COVID-19 pandemic, a disease caused by a novel virus called SARS-CoV-2. Some authors have described the ultrasonographic findings of COVID-19 pneumonia in adults and children, but data on neonates are lacking. Our objective was to describe the ultrasonographic lung pattern on newborns with SARS-CoV-2 infection during the COVID-19 pandemic. Newborns who tested positive for SARS-CoV-2 PCR in respiratory samples and were evaluated with point-of-care lung ultrasound (LU) from March to April 2020 were included. LU was performed bedside by a single investigator at the time of diagnosis and every 48 h during the first week following diagnosis. Six areas were studied. Three neonates were included. Infants' comorbidities included meconium aspiration syndrome, bronchopulmonary dysplasia, and Hirschsprung's disease. One required mechanical ventilation. No deaths occurred. LU showed B-lines, consolidation, and spared areas. No pneumothorax or pleural effusion was observedConclusions: LU could be of value when managing COVID-19 neonates. We describe the findings of lung ultrasound monitoring during the first week following diagnosis in three neonates with SARS-CoV-2 infection. What is known: ⢠Lung ultrasound (LU) is a useful tool in COVID-19 management in adults. To date, no report on LU and neonates with SARS-CoV-2 infection has been published. What is new: ⢠This study adds evidence about LU findings in neonates with SARS-CoV-2 infection.
Assuntos
Betacoronavirus , Técnicas de Laboratório Clínico/métodos , Infecções por Coronavirus/diagnóstico por imagem , Pulmão/diagnóstico por imagem , Pneumonia Viral/diagnóstico por imagem , Sistemas Automatizados de Assistência Junto ao Leito , COVID-19 , Teste para COVID-19 , Infecções por Coronavirus/complicações , Infecções por Coronavirus/diagnóstico , Humanos , Recém-Nascido , Masculino , Pandemias , Pneumonia Viral/complicações , SARS-CoV-2 , UltrassonografiaRESUMO
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Assuntos
Masculino , Lactente , Humanos , Melanose/diagnóstico , Melanose/terapia , Hiperpigmentação/complicações , Hiperpigmentação/diagnóstico , Fundo de Olho , Infecções Oculares/diagnóstico , Infecções Oculares/terapia , Nevo/complicações , Síndrome do Nevo Displásico/complicações , Síndrome do Nevo Displásico/diagnóstico , Melanócitos/patologia , Melanoma/complicações , Melanoma/diagnóstico , Olho/patologia , Olho/fisiopatologiaRESUMO
Burkholderia cepacia is a Gram-negative bacillus that is widely distributed in nature; it is isolated from the ground, water, plants and vegetables. Generally, it produces nosocomial infection due to contamination of disinfectants, medical equipment, prosthetic material and drugs, such as anesthetics or liquids used in urological irrigation. The most probable mechanism of transmission is through hospital material or through fomites among people after contact for several weeks or months. Recently, it has been considered as an important pathogen in immunocompromised patients, or in those with significant underlying diseases, such as chronic granulomastosis or cystic fibrosis. We present a case of pharyngitis due to B. cepacia and its transmission within a few days in two immunocompetent twin siblings without previous underlying diseases. The infection disappeared after specific treatment for this microorganism was started. We believe that samples should be taken from the pharynx and nasal pits in patients with acute upper respiratory tract processes that do not respond to empiric antibiotic treatment, before classifying them as viral infection without etiologic diagnosis.
Assuntos
Infecções por Burkholderia/transmissão , Burkholderia cepacia , Doenças em Gêmeos , Faringite/microbiologia , Infecções por Burkholderia/diagnóstico , Burkholderia cepacia/isolamento & purificação , Humanos , Imunocompetência , Lactente , MasculinoRESUMO
Burkholderia cepacia es un bacilo gramnegativo que se encuentra ampliamente distribuido en la naturaleza, y se aísla del suelo, el agua y las plantas y verduras. Generalmente produce infección nosocomial por contaminación de desinfectantes, equipos médicos, material protésico y fármacos, como anestésicos o líquidos de irrigación urológicos. El mecanismo de transmisión más probable es a través del material hospitalarios o de fomites entre personas tras un contacto de varias semanas o meses. Recientemente, se ha considerado como un patógeno importante en pacientes inmunodeprimidos o con enfermedades de base importantes, como la granulomatosis crónica y la fibrosis quística. Se presenta el caso de una faringitis por B. cepacia y su transmisión en pocos días en dos hermanos gemelos, inmunocompetentes y sin enfermedades de base previas y, la desaparición de la enfermedad tras la instauración de un tratamiento específico para este microorganismo. Consideramos que se deben tomar muestras de faringe y fosas nasales ante un proceso agudo del tracto respiratorio superior que no responde al tratamiento antibiótico empírico, antes de clasificarlo como viriasis sin diagnóstico etiológico (AU)
