Self-disclosure of breast cancer diagnosis by Iranian women to friends and colleagues.

BACKGROUND: Breast cancer (BC) is the most common form of cancer in Iranian women, and it remains a major health problem. An increasing number of young women are being diagnosed with BC, and therefore, there is an increasing likelihood that more women will survive breast cancer for many years. Many opine that self-disclosure of BC diagnosis is important because talking about cancer helps people to make sense of their experiences; in fact, self-disclosure appears to play an important role in many health outcomes. However, this has not yet been studied in BC patients in Iran. Therefore, this study aimed to explore the status of self-disclosure of BC diagnosis by Iranian women to friends and colleagues. MATERIALS AND METHODS: All BC records for 2001-2011 of employed women were studied at five hospitals in Mashhad. Data about the self-disclosure of BC diagnosis were gathered through telephone interviews, and the participants filled out a questionnaire about their status of self-disclosure of BC diagnosis to various groups of people. RESULTS: The mean age of employed women at the time of diagnosis was 44.3 ± 6.7 years. Over 60% self-disclosed to work colleagues and over 90% to bosses/managers. Seventy per cent reported that they had support from their family and husband's family, while 95% reported that they had support from parents, siblings, children and friends. CONCLUSIONS: Most employed women self-disclosed freely to family, friends, colleagues and bosses/managers. Apparently, self-disclosure of breast cancer diagnosis may have negative effects at work. About half of patients reported that they had support from family, managers and colleagues; however, for nearly 28% of employed women, disclosure had less positive effects. In particular, it altered their perception of others, produced difficulties with work and family and diminished closeness with the people who were told. However, the stigma of BC is far less than it once was.

Lifelong physical activity affects mini mental state exam scores in individuals over 55 years of age.

INTRODUCTION: The positive effects of physical activity on cognition have been widely documented. Human studies and the results obtained from animal models of Alzheimer's disease (AD) have shown that if commenced early in life, exercise effectively reduces the development of cognitive deficits caused by aging. In the present study, the scores on Mini Mental State Exam (MMSE) of individuals over 55 years old who had a history of exercising have been compared to those without a history of exercising. METHODS: This research was carried out on 273 individuals over 55 years of age. The subjects were randomly chosen from different areas of Mashhad and from exercise clubs. Each person completed a personal information form containing data such as demographics in addition to details of their involvement in sporting activity. Subjects were categorized as follows: 1- non-exercised, 2- exercised. The people in group 2 were then divided into non-professionally exercised (with a history of 2-10 years exercising) or professionally--exercised subjects (i.e. people who were currently, or had previously been members of an exercise club and/or had been trained for at least 10 years). RESULT: Out of 273 subjects questioned in the present study, 229 were males and 44 were females. The MMSE score in men was significantly higher than women (p < 0.001). The exercised individuals of both sexes had significantly higher scores compared to non-exercised group (p < 0.001). There was no significant difference between professionally- exercised individuals of either sex in comparison with exercised ones. CONCLUSION: It is suggested that lifelong physical activity and exercise affects cognitive performance in old age.

Changes in pro-oxidant-antioxidant balance after bare metal and drug eluting stent implantation in patients with stable coronary disease.

OBJECTIVES: In this study we aimed to assess the changes in pro-oxidant-antioxidant balance (PAB) after the placement of either a drug-eluting-stent (DES) or bare-metal-stent (BMS) in patients with stable coronary artery disease. DESIGN AND METHODS: Percutaneous coronary interventions (PCI) with either BMS or DES were undertaken for 152 patients (82 in the BMS and 70 in the DES groups respectively). PAB values were measured 24h before and after PCI. RESULTS: Baseline PAB values were 80.68 (64.98-99.37) and 98.86 (64.70-140.62) for BMS and DES group, respectively, which were not significantly different between the 2 groups (P>0.05). Following PCI, median PAB values decreased to 72.10 (61.40-96.13) and 81.40 (54.15-121.90) in BMS and DES groups, respectively. The reduction was significant in both BMS and DES groups (P<0.05). The changes in PAB values were -2.81 (-12.76 to 2.31) for BMS and -2.82 (-29.88 to 8.93) for DES group, which were not significantly different between the 2 groups (P>0.05). CONCLUSION: We found that the reported difference in clinical outcomes following DES or BMS implantation cannot be attributed to differences in early changes in oxidative stress induction as assessed by changes in PAB values.

Oral cancer knowledge among patients referred to Mashhad Dental School, Iran.

BACKGROUND: Early intervention improves treatment results in oral cancer. The purpose of present study was to assess the level of awareness and knowledge about oral cancer among patients referred to Mashhad Dental School. METHODS: Three hundred and twenty individuals completed a 15 item written questionnaire that focused on oral cancer risk factors, signs and symptoms, epidemiology, and treatment. Statistical analyses were performed with the Kruskal-Wallis and Friedman tests (level of significance, P=0.05). RESULTS: A total of 89.4% of patients who completed the questionnaire had a poor understanding of oral cancer, particularly with regard to etiology. Additionally, 83.8% were unaware of oral cancer risk factors. Only 8.8% knew the most likely sites for oral cancer. No relation was identified between knowledge and sex (P=0.01), or age (P=0.052) of the subjects. There was a significant correlation between the level of education and knowledge score (P<0.001). Medical students and health professionals had the highest knowledge scores (P<0.001). CONCLUSION: According to the results of this study, information regarding oral cancer knowledge is quite low. Therefore, it seems necessary to increase the level of public awareness with the use of various educational programs in order to reduce morbidity and mortality.

Metabolic syndrome may not be a good predictor of coronary artery disease in the Iranian population: population-specific definitions are required.

The inability of two definitions of metabolic syndrome (MS) to predict the presence of coronary artery disease (CAD) in a non-Caucasian population was demonstrated. Angiography was used as the gold standard method for identifying patients with (cases) or without (controls) CAD. It is possible that the current definitions of MS are not appropriate for some non-Caucasian populations.