RESUMO
Herpes gestationis is a rarely seen autoimmune vesiculobullous and pruritic dermatosis of pregnancy. Neonatal morbidity associated with maternal herpes gestationis is controversial. The authors report the first case of neonatal convulsion with abnormal electroencephalography findings and transient vesicular eruption due to maternal herpes gestationis.
Assuntos
Doenças Fetais , Penfigoide Gestacional/fisiopatologia , Convulsões/etiologia , Adulto , Doenças Autoimunes , Feminino , Humanos , Mães , Penfigoide Bolhoso/etiologia , Penfigoide Bolhoso/patologia , Gravidez , Resultado da Gravidez , Convulsões/patologia , Dermatopatias Vesiculobolhosas/etiologiaRESUMO
We describe a newborn infant with defects similar to those seen in mice heterozygous for the mutant disorganization (Ds) gene. The child had left popliteal webbing, left iliac bone hypoplasia, bifid scrotum, hypospadias, chordee deformity of the penis and a sacral dimple. Other anomalies included absence of the right kidney and a bizarre hamartomatous tubular skin pedicle on the left thigh. No obvious amniotic bands or oligohydramnios were noted. The similarity between the proband's anomalies, those in previously reported cases, and those found in mice support the possibility of a human homologue of the Ds gene.
