RESUMO
OBJECTIVE: Hypopharyngeal carcinoma is an aggressive malignancy usually diagnosed at a late state, thereby resulting in overall poor prognosis and low survival rates for these patients. The purpose of this study is to present the progress and outcomes of patients treated for hypopharyngeal carcinoma at our department. MATERIAL AND METHOD: We retrospectively reviewed 89 patients who had been diagnosed with hypopharygeal carcinoma between 1980 and 2005. Most of the tumours were advanced (T3 and T4) and 73 % showed palpable regional metastases at presentation. RESULTS: The five-year survival rate was 40.7 %. The overall incidence of distant metastases and subsequent primary neoplasms was 7.5 % and 23.5 %, respectively. CONCLUSIONS: Hypopharyngeal cancer is still the one with the worst prognosis in the head and neck area. The poor survival rate seems to be related primarily to advanced stage disease at presentation and particularly to the status of cervical lymph-node metastases.
Assuntos
Neoplasias Hipofaríngeas/terapia , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Neoplasias Hipofaríngeas/patologia , Masculino , Pessoa de Meia-Idade , Metástase Neoplásica , Recidiva Local de Neoplasia/epidemiologia , Estudos Retrospectivos , Taxa de SobrevidaRESUMO
Objetivo: el cáncer de hipofaringe es un cáncer muy agresivo que generalmente se diagnostica en estadios muy avanzados, su pronóstico es desalentador y la tasa de supervivencia, muy baja. El objetivo de este estudio es presentar la evolución y los resultados de los pacientes tratados de cáncer de hipofaringe en nuestro servicio. Material y método: realizamos un estudio retrospectivo en 89 pacientes diagnosticados de cáncer de hipofaringe entre los años 1980 y 2005. En su mayoría se trataba de tumores avanzados (T3 y T4) y el 73 % presentaba adenopatías palpables en el momento del diagnóstico. Resultados: la supervivencia a los 5 años fue del 40,7 %. Encontramos una incidencia de metástasis a distancia y segundos tumores primarios de un 7,5 y un 23,5 %, respectivamente. Conclusiones: el carcinoma de hipofaringe continúa siendo el cáncer de cabeza y cuello de pronóstico peor. La tasa de supervivencia parece estar relacionada primariamente con el estadio tumoral de presentación y, de forma particular, con el estado de los ganglios linfáticos cervicales (AU)
Objective: hypopharyngeal carcinoma is an aggressive malignancy usually diagnosed at a late state, thereby resulting in overall poor prognosis and low survival rates for these patients. The purpose of this study is to present the progress and outcomes of patients treated for hypopharyngeal carcinoma at our department. Material and method: We retrospectively reviewed 89 patients who had been diagnosed with hypopharygeal carcinoma between 1980 and 2005. Most of the tumours were advanced (T3 andT4) and 73 % showed palpable regional metastases at presentation. Results: The five-year survival rate was 40.7 %. The overall incidence of distant metastases and subsequent primary neoplasms was 7.5 % and 23.5 %, respectively. Conclusions: Hypopharyngeal cancer is still the one with the worst prognosis in the head and neck area. The poor survival rate seems to be related primarily to advanced stage disease at presentation and particularly to the status of cervical lymph-node metastases (AU)
