RESUMO
Evidences suggest that a diet rich in fruits and vegetables decreases the risk of several degenerative diseases. The world population aging process requires more efforts to delay the onset of such diseases. Therefore, the inclusion of functional foods in the diet is an excellent strategy to improve the quality of life. Brazil is the world`s largest producer of orange, which provides many health benefits. The purpose of this paper is to review the recent literature in order to demonstrate the benefits provided by the inclusion of orange in the diet as a preventive measure for many diseases. Based on the properties demonstrated in this review, a discussion about the inclusion of orange in the category of functional foods is proposed.
Las evidencias sugieren que una dieta rica en frutas y hortalizas reduce el riesgo de varias enfermedades degenerativas. El envejecimiento de la población mundial exige más esfuerzos para retardar la manifestación de esas enfermedades. Por lo tanto, la inclusión de alimentos funcionales en la dieta es una excelente estrategia para mejorar la calidad devida de poblaciones. La naranja, que encuentra en Brasil su mayor productor mundial, tiene varias propiedades benéficas para la salud. El propósito de este trabajo fue revisar la literatura reciente para demostrar los beneficios de la inclusión de naranja en la dieta como medida preventiva de una serie de enfermedades. Con base en las propiedades demostradas e nesta revisión, se propone discutir la inclusión de la naranja en la categoría de alimentos funcionales.
As evidências sugerem que uma dieta rica em frutas e vegetais reduz o risco de várias doenças degenerativas. O envelhecimento da população mundial requer mais esforços no sentido de retardar o aparecimento deste tipo de doença. Portanto, a inclusão de alimentos funcionais na dieta é uma excelente estratégia para melhorar a qualidade de vida da população. A laranja, fruta que tem o Brasil, como o seu maior produtor mundial, possui diversas propriedades benéficas à saúde. O propósito deste artigo é revisar a literatura recente demonstrando os inúmeros benefícios da inclusão da laranja na dieta, como medida preventiva de uma série de doenças. Com base nas propriedades demonstradas nesta revisão, propõe-se a discussão sobre a inclusão da laranja na categoria de alimento funcional.
Assuntos
Citrus sinensis/metabolismo , Alimento Funcional , Ácido Ascórbico/biossíntese , Ácido Ascórbico/uso terapêutico , Prevenção de Doenças , Flavonoides , FrutasRESUMO
BACKGROUND: The eradication of early stage neoplastic lesions in Barrett's esophagus is imperative to prevent invasive adenocarcinoma. Early stage lesions have an extremely low risk of lymph node metastasis, thereby, making local treatment feasible. Photodynamic therapy destroys malignant cells by a photochemical effect. The aims of this study were to evaluate the efficacy and tolerance of photodynamic therapy with green light and a new photosensitizer, temoporfin or m-tetrahydroxyphenyl chlorin in patients with Barrett's esophagus and early stage neoplastic lesions. METHODS: Four days after injection of m-tetrahydroxyphenyl chlorin, lesions were illuminated at a wavelength of 514 nm through non-circumferential windowed diffusers. Follow-up endoscopy with biopsies was performed at regular intervals. RESULTS: Fourteen lesions (7 high-grade dysplasia, 7 intramucosal adenocarcinoma) in 12 patients were treated. For all lesions, efficacy was 100% and squamous re-epithelialization was complete. Side effects were of moderate severity (one stricture). Mean follow-up was 34 (15) months (range 12-68 months). CONCLUSIONS: Green light photodynamic therapy with m-tetrahydroxyphenyl chlorin can eradicate early stage neoplastic lesions in Barrett's esophagus and may be proposed as an alternative first-line therapy or a second-line therapy after failure of other endoscopic treatments. The efficacy and patient tolerance of the procedure justify further studies of the method in larger groups of patients.
