Food for thought on eating while meeting virtually.

This study examines observers' perceptions of employees eating during virtual work meetings. Using a 2 × 3 experimental design, participants (N = 842) were randomly assigned to one of three eating conditions including no one eating, target eating, and everyone eating where they rated either a male or female target. While existing research has demonstrated positive consequences of sharing food in the traditional workplace, our findings demonstrate that individuals who eat during virtual work meetings are perceived as less professional, less competent, and less likely to experience career success. Observers' perceptions of the eater's professionalism are negatively impacted, regardless of whether the target is the only one eating or whether everyone is eating. We offer practical suggestions for HRM professionals working to help managers and employees understand the nuances of videoconferencing.

Ipomoeassin F, a new cytotoxic macrocyclic glycoresin from the leaves of Ipomoea squamosa from the Suriname rainforest.

A new cytotoxic macrocyclic glycoresin, ipomoeassin F (6), has been isolated from the leaves of Ipomoea squamosa. The structure was elucidated by the interpretation of spectral data. Compound 6 was strongly active in the A2780 (human ovarian cancer cell line) assay with an IC(50) value of 0.036 microM.

Ipomoeassins A-E, cytotoxic macrocyclic glycoresins from the leaves of Ipomoea squamosa from the Suriname rainforest.

The new glycoresins, ipomoeassins A-E (1-5), have been isolated from the leaves of Ipomoea squamosa. The structures were elucidated by spectroscopic analyses and chemical transformations. The absolute configurations of C-5 (ipomoeassins 3-5) and C-11 (ipomoeassins 1 and 2) were determined by their derivatives with (R)- and (S)-MPA. All the isolates were active in the A2780 human ovarian cancer cell line assay, and 4 showed the highest activity with an IC(50) value of 35 nM.

A novel cytotoxic guttiferone analogue from Garcinia macrophylla from the Suriname rainforest.

Bioassay-guided fractionation of the EtOAc extract of the twigs of Garcinia macrophylla from Suriname produced the known benzophenone, guttiferone A (1), and a new guttiferone analogue, guttiferone G (2). Friedelin was also isolated. The structures of compounds 1 and 2 were elucidated using 1D and 2D NMR spectroscopy. Compounds 1 and 2 were weakly cytotoxic in the A2780 human ovarian cell line, with IC (50) values of 6.8 and 8.0 microg/mL, respectively.