[Knowledgebase as a tool for monitoring post-genomic medico-biological research].

On-going molecular biological researches are characterized by exponential increase in the amount of experimental data which dictates the necessity to develop relevant information technologies. The knowledge-based approach appears to be a most promising and flexible tool for analytical processing biomedical information that allows new relationships between study objects to be established. In this article we analyze the work of researchers based at the Institute of Biomedical Chemistry with the materials of the PubMed biomedical library. A list of publication IDs for a half-year period has been compiled to elucidate individual profiles of research activities. Statistical analysis of medical subject headings (MeSH) reveals typical profiles of research of interest for separate divisions of the Institute. The proposed approach may be recommended as a means for improving the efficiency and coordination of biomedical research.

[Knowledgebases in postgenomic molecular biology].

Knowledgebases can become an effective tool essentially raising quality of information retrieval in molecular biology, promoting the development of new methods of education and forecasting of the biomedical R&D. Knowledge-based technologies should induce "paradigm shift" in the life science due to integrative focusing of research groups towards the challenges of postgenomic era. This paper debates concept of the knowledgebase, which exploits web usage mining to personalize the access of molecular biologist to the Internet resources.