RESUMO
This paper reports the chest X-rays, Heaf tests and haematology findings on a population of Gurkha wives and their children who arrived in the UK to accompany their husbands on an army base in 1997-8. The conclusions from this study are that there is no benefit from performing chest X-rays, but that screening for rubella and iron deficiency anaemia should continue.
Assuntos
Emigração e Imigração , Testes Hematológicos/normas , Radiografia Pulmonar de Massa/normas , Programas de Rastreamento/métodos , Programas de Rastreamento/normas , Militares , Testes Sorológicos/normas , Teste Tuberculínico/normas , Adolescente , Adulto , Criança , Redução de Custos , Análise Custo-Benefício , Feminino , Testes Hematológicos/economia , Hong Kong/etnologia , Humanos , Masculino , Radiografia Pulmonar de Massa/economia , Programas de Rastreamento/economia , Nepal/etnologia , Avaliação de Programas e Projetos de Saúde , Testes Sorológicos/economia , Teste Tuberculínico/economia , Reino UnidoRESUMO
Using two random DNA markers, and pulsed field gel electrophoresis, a 1.5-Mb physical map surrounding the 11p13 aniridia locus (AN2) has been assembled. The map was constructed using a combination of single- and double-restriction digests on DNA from normal controls and a patient transmitting familial aniridia. The aniridia patient has a chromosome translocation and the two DNA markers flank the breakpoint. This 11p13 breakpoint lies no further than 100 kb from the DNA marker 1104 (D11S95), located on the centromeric side of the breakpoint. Two CpG islands, separated by 550 kb and flanking the translocation, suggest an upper limit to the size of the gene.
