RESUMO
Endometritis is considered as one of the main causes of subfertility and infertility in mares, having a great economic impact on equine industry. Chronic uterine infections resistant to antimicrobial agents can be causedd ue to the production of biofilm. Phytoterapy products provide a great potential for the production of new drugs due to their structural diversity. Schinus terebinthifolius, is a plant with antiseptic and anti-inflammatory. In clinical studies, its therapeutic action has been proven in cervicitis and chronic cervical-vaginitis in women. Thus, the objective of this work was to evaluate in vitro the growth in clinical bacterial isolates, production of biofilm and its breakdown against different concentrations of a medication based on Schinus terebinthifolius (Kronel®). As a result, a numeric reduction in bacterial growth was observed, as well as a partial break in the biofilm directly proportional to the concentration of Schinus terebinthifolius used. Different activities were also found according to bacteria tested. Despite being preliminary data, it was possible to observe a positive action both in the inhibition of growth and in the partial breakdown of a natural commercial product obtained from Schinus terebinthifolius in the bacterial treatment in vitro.(AU)
Assuntos
Animais , Feminino , Endometrite/diagnóstico , Endometrite/tratamento farmacológico , Endometrite/veterinária , Fitoterapia/veterináriaRESUMO
Endometritis is considered as one of the main causes of subfertility and infertility in mares, having a great economic impact on equine industry. Chronic uterine infections resistant to antimicrobial agents can be causedd ue to the production of biofilm. Phytoterapy products provide a great potential for the production of new drugs due to their structural diversity. Schinus terebinthifolius, is a plant with antiseptic and anti-inflammatory. In clinical studies, its therapeutic action has been proven in cervicitis and chronic cervical-vaginitis in women. Thus, the objective of this work was to evaluate in vitro the growth in clinical bacterial isolates, production of biofilm and its breakdown against different concentrations of a medication based on Schinus terebinthifolius (Kronel®). As a result, a numeric reduction in bacterial growth was observed, as well as a partial break in the biofilm directly proportional to the concentration of Schinus terebinthifolius used. Different activities were also found according to bacteria tested. Despite being preliminary data, it was possible to observe a positive action both in the inhibition of growth and in the partial breakdown of a natural commercial product obtained from Schinus terebinthifolius in the bacterial treatment in vitro.