Puberty in modernizing Kazakhstan: a comparison of rural and urban children.

BACKGROUND: Data on puberty development are available for several countries but not for Central Asia. AIM: Using data collected during the Kazakhstan Health and Nutrition Survey (KHA-ES), we evaluated the relationship between the living environment (rural vs. urban), ethnicity (Russians vs. Kazakhs) and pubertal status in children living in Kazakhstan. SUBJECTS AND METHODS: Genital (G1-G5), breast (B1-B5) and pubic hair (PH1-PH5) development were evaluated in a sample of 2389 boys and 2416 girls using Tanner's criteria. Age at menarche was evaluated using the 'status quo' and 'recall' methods. RESULTS: Rural children were older than urban children at stages > or =G2 for males and > or =B2 for females, and this difference was more evident for Russian males. Differences levelled out at later stages of development in Kazakh males and in the pooled girls. The living environment was slightly but significantly associated with median age at menarche (12.89 years for urban Kazakhs to 13.43 years for rural Kazakhs). Male and female Kazakhs were older than Russians at stages 4 and 5, especially in the urban area. CONCLUSION: A relationship between pubertal status and the living environment was present in a rapidly modernizing country such as Kazakhstan.

Spirometric reference values for children and adolescents from Kazakhstan.

BACKGROUND: Spirometric parameters are influenced by several factors and many reference data are available in the literature. However, no spirometric data are available for children and adolescents from Central Asia. AIM: The study aimed to calculate spirometric reference curves on the basis of anthropometry, ethnicity (Kazakh vs. Russian) and living environment (urban vs. rural). SUBJECTS AND METHODS: Spirometry (FEV1, FVC and FEF25-75%) was performed and anthropometric measurements taken for 1926 male and 1967 female Kazakh children aged 7-18 years. RESULTS: Height explained almost all the variance of forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1) for both sexes, while age and inspiratory circumference contributed slightly to the prediction. Moreover, FVC and FEV1 were greater in Russians than in Kazakhs and ethnicity did enter the prediction model for these parameters. The living environment had a marginal effect on spirometry. In fact, forced expiratory flow 25-75% (FEF25-75%) was slightly higher in urban than in rural females, FVC was slightly higher in rural than in urban males, while FEV1 was not affected. Finally, among several spirometric equations available in the literature, those performing better in our children were obtained in developed countries. CONCLUSION: Anthropometry was the most important predictor of spirometry. Age and ethnicity were also predictors, while the contribution of the living environment was more limited.

Prevalence of overweight and cardiovascular risk factors in rural and urban children from Central Asia: the Kazakhstan health and nutrition examination survey.

Kazakhstan is undergoing a rapid modernization process, which carries the risk of an epidemic of obesity and cardiovascular disease. We enrolled a sample of about 50 children for every combination of gender, environment (urban vs. rural), ethnic group (Kazakh vs. Russian), and age group from 7 to 18 years, for a total of 4,808 children. Anthropometry and blood pressure were measured on all children while fasting blood cholesterol and glucose were measured only in 2,616 children aged > or =12 years. The prevalence of overweight and risk of overweight ranged from 2.8 (rural male Kazakhs) to 9.1% (urban male Russians). The prevalence of prehypertension and hypertension ranged from 8.3 (urban females) to 15.9% (rural females); that of hypercholesterolemia from 11.5 (male rural Russians) to 26.5% (female rural Kazakhs); and the overall prevalence of impaired fasting glucose was 0.1%. We conclude that overweight and cardiovascular risk factors are less prevalent in children living in Kazakhstan than in those living in Western countries. However, these figures are not negligible and suggest that preventive measures are needed to contain the epidemic of overweight and cardiovascular disease that will most likely accompany the modernization of Kazakhstan in the next years.

The study of entheses: proposal of a standardised scoring method for twenty-three entheses of the postcranial skeleton.

Entheses are always visible on the bone, although with variable forms and degrees of expression. The term "robusticity" indicates the "normal" osseous markings at entheses, while "enthesopathy", indicates the presence of enthesophytes or osteolytic areas. A scoring method for enthesopathy development has already been proposed. In this paper, a standardised descriptive and photographic scoring method is proposed for the robusticity of 23 postcranial skeleton entheses. For each enthesis, 3 levels of development are described, corresponding, in general, to a weak-moderate expression (degree 1), strong development (degree 2) and very strong development (degree 3). The interobserver error of about 20% seems acceptable given the great morphological variability of these traits.

Continuity or discontinuity of the life-style in central Italy during the Roman Imperial Age-Early Middle Ages transition: diet, health, and behavior.

Dento-alveolar pathologies and alterations (dental wear, caries, abscesses, ante mortem tooth loss (AMTL), calculus, hypoplastic defects, and chipping) and skeletal markers of health (cribra orbitalia and periostitis) were analyzed in two skeletal samples from the necropolises of Quadrella (I-IV c. AD) and Vicenne-Campochiaro (VII c. AD) in the Molise region of central Italy. The aim was to determine if the Roman Imperial Age-Early Middle Ages transition characterized by political, socioeconomic, and cultural transformations affected the biology of these populations, particularly their alimentation and health status. The frequencies of caries and AMTL, similar in the two samples, suggest a high consumption of carbohydrates. The higher levels of heavy wear, calculus, and interproximal chipping in the Vicenne population indicate a greater use of fibrous foods (both meat and others), in line with the dietary model of Germanic peoples. Health conditions do not appear to have been good in either period, as shown by the high frequencies of linear hypoplasia and the presence of cribra orbitalia and periostitis. The diet of the individuals buried with horses of the Vicenne population did not differ from that of the rest of the population, whereas there were evident differences in the use of the teeth for nonmasticatory activities among these individuals. Therefore, from the point of view of alimentation and health status, the profound socioeconomic and cultural transformations during the Late Antiquity-Early Middle Ages transition do not seem to have been translated into a true discontinuity of the two Molisan populations.

Age determination on long bones in a skeletal subadults sample (b-12 years).

The skeletal age on the basis of the diaphyseal length of long bones was assessed. To this aim a sample of subadults skeleton, dated to last century, coming from the cemetery of Bologna was studied. The sample is composed by 79 males and 70 females between 0 and 12 years, whose chronological age and sex are known. Some information can be obtained by the means, standard deviation and graphs of the specimens grouped in age classes. The comparison with other studies confirms the interest of using standards based on direct measurements on long bones of known age and similar to the skeletal populations under study.

Enthesopathies--proposal of a standardized scoring method and applications.

Enthesopathies are alterations that could be present at entheses. Two types of enthesopathies have been defined: osteophytic (OF) and osteolytic (OL). In the present paper, we propose a standardized method to score the degree of development of each form of enthesopathy. With this method, the intra- and interobserver errors are less than 50%. The standard was used to study a sample (113 individuals) deriving from osteological collections from the late XIX-early XX century. Information about the age, sex and occupation of the individuals is available. This study demonstrated an effect of age on the form and the degree of development of enthesopathies. The influence of factors related to sex and occupation cannot be excluded. Therefore, functional interpretations of data on enthesopathies in osteoarchaeological series must take account of the estimated age and sex of the specimens and the distribution of the lesions within a single skeleton.

Proposal of a data collection form to record dento-alveolar features--application to two Roman skeletal samples from Italy.

Bones and teeth are an important source of information about the lifestyle, health status and dietary habits of past populations. Modifications and lesions of the periodontal tissues also provide information about the health status and behavior of an individual or of an ancient population. In this paper a method to record some dento-alveolar features of both deciduous and permanent teeth is described. The forms that we propose make it easy to record the data in a Microsoft Excel sheet. The form for adults has been applied to two Roman Imperial age skeletal samples from northern Italy - Casalecchio di Reno (II-V c. AD, Bologna) and Emilia Romagna, and central Italy - Quadrella (I-IV c. AD, Isernia, Molise).

Is elbow breadth a measure of frame size in non-Caucasian populations? A study in low- and high-altitude Central-Asia populations.

UNLABELLED: The concept of frame size has not undergone a thorough evaluation in non-Caucasian populations. Using data from the Central Asia High Altitude Population (CAHAP) study, we tested whether: (1) the relationship between frame size and body composition is different in high-, medium- and low-altitude populations; (2) elbow breadth is a better index of frame size than biacromial and biiliac breadth; and (3) measures of frame size are associated with blood pressure, cholesterol and triglycerides. A number of 334 male subjects aged 33 +/- 10 years (mean +/- standard deviation) were selected from the CAHAP population (n = 384) on the basis of the availability of breadth measurements. The subjects were 85 high-altitude Kirghizs, 105 medium-altitude Kazakhs, 79 low-altitude Kirghizs and 65 low-altitude Uighurs. A detailed anthropometric evaluation and blood pressure, cholesterol and trygliceride measurements were performed on all individuals. Among breadths, elbow had the lowest correlation with arm fat area, thigh fat area, calf fat area and the sum of trunk skinfolds (r < or = 0.196, P < 0.01). Even if elbow breadth did not have the highest correlation with muscularity indexes, its constantly lower association with adiposity indexes shows that it is a better measure of frame size than biacromial breadth and biiliac breadth. The relationship between frame size and body composition did not differ in high-, medium- and low-altitude subjects (P = not significant, analysis of co-variance). Only a weak association was present between breadths, blood pressure, cholesterol and triglycerides (r < or = 0.230, P < 0.01) and it was not influenced by altitude (P = not significant, analysis of co-variance). Elbow breadth was significantly correlated only with diastolic blood pressure (r = 0.121, P < 0.05). IN CONCLUSION: (1) the relationship between frame size and body composition is similar in high- and low-altitude populations; (2) elbow breadth is an index of frame size independent of altitude; and (3) elbow breadth is correlated with diastolic blood pressure, but this correlation is of doubtful biological relevance.