1.
Org Lett
; 15(15): 3812-5, 2013 Aug 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23859310
RESUMO
Methyl 2-acetamidoacrylate reacted with various 2-substituted indoles in the presence of catalytic amounts of AgSbF6 or AuPPh3NTf2 to provide the corresponding methyl 2-(2-substituted-1H-indol-3-yl)acrylates.
Assuntos
Acrilatos/química , Acrilatos/síntese química , Ouro/química , Indóis/química , Indóis/síntese química , Prata/química , Catálise , Estrutura Molecular
2.
J Org Chem
; 77(22): 10461-7, 2012 Nov 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23088773
RESUMO
Two unprecedented oxygenated aaptaminoids have been synthesized starting from cheap and easily available 2,3-dihydroxybenzoic acid with the satisfactory overall yields of 31% and 34%. The key step of the procedure is the divergent thermic 5-exodig vs base-promoted 6-endodig cyclization of a 5-alkynylquinolinone derivative.