[Metabolic bone tissue markers dynamics as criteria for periodontal disease treatment efficiency]. / Izmenenie pokazatelei metabolizma kostnoi tkani kak kriterii effektivnosti lecheniya generalizovannogo parodontita.

The purpose of the study was to investigate the evolution of the tissue metabolism parameters in the course of the treatment of aggressive periodontitis forms. MATERIALS AND METHODS: The paper presents the results of the treatment of 68 patients with chronic generalized periodontitis. The control group comprised 10 healthy individuals. The patients of groups 1 and 3 were treated with metronidazole placement into gingival pockets; those of groups 2 and 4 received a mixture of metronidazole and Eplan. General therapy of group 1 and 2 included treatment with Calcemin, while that of group 3 and 4 alendronate and alphacalcidolum based medicine. Treatment efficiency was assessed by clinical signs, alkaline phosphatase level activity in the oral fluid, as well as serum levels of general and a ionized calcium, phosphorous, alkaline phosphatase and and osteocalcin. RESULTS: The test results before treatment showed higher level of the alkaline phosphatase and osteocalcin in the blood of the patients with periodontitis vs. controls. In the course of follow up group 4 patients showed a clinical response already on the 3rd day of treatment, activization of osteogenesis and bone tissue mineralization in 3 months, and a recovery of the bone metabolism markers in 12 months after local application of Eplan and intake of alendronate and alphacalcidolum based medicine. CONCLUSION: The proposed therapy using Eplan and alendronate and alphacalcidolum based medicines increases the efficiency of periodontitis therapy, which allows for a faster relief of inflammation of periodontal tissues, bone tissue mineralization, long-term and sustainable disease regression.

[Evaluation of the hazard of soil-polluting chemicals upon exposure of experimental animals].

The experimental study of the biological activity of the modified calcium chloride produced by a Volgograd plant and that of ash-and-slag of the pharmaceuticals resulting after combustion of a pyrolytic mixture of filtration burning could establish various hazards of these substances.

[Morphological assessment of physical methods of dissection and coagulation in operations on the stomach]. / Morfologicheskaia otsenka fizicheskikh sposobov dissektsii i koaguliatsii pri operatsiiakh na zheludke.

The first results of experimental investigation of the potencies of a new domestic electrosurgical apparatus "ESA-MINI-01" are presented. The investigation of the morphological alterations in the stomach wall after using different physical methods of dissection and coagulation has proved the advantages of the new apparatus which has the principle of work based on an original means of forming the outlet parameters.

[Clinico-morphological evaluation of physical methods of dissection and coagulation in stomach surgery (a preliminary report)]. / Kliniko-morfologicheskaia otsenka fizicheskikh sposobov dissektsii i koaguliatsii pri operatsiiakh na zheludke (predvaritel'noe soobshchenie).

The article presents preliminary results of experimental investigations of clinico-morphological alterations in the gastric wall occurring during operations on the stomach performed with using high frequency electrosurgical apparatuses. The authors stress the expedience of using the apparatuses with the working frequency of electric current higher than 3 MHz for the abdominal surgery.