Clinical utility of transient elastography as an imaging tool to assess the short-term impact of laparoscopic sleeve gastrectomy, together with clinical and biochemical parameters and clinico-biochemical indices, on obese patients with nonalcoholic fatty liver disease: An Egyptian pilot study. / La utilidad clínica de la elastografía transitoria como una herramienta de imagenología para evaluar el impacto a corto plazo de la gastrectomía laparoscópica en manga, en conjunto con parámetros clínicos y bioquímicos e índices clínico-bioquímicos en pacientes con enfermedad de hígado graso no alcohólico: un estudio piloto egipcio.

INTRODUCTION: Nonalcoholic fatty liver disease (NAFLD) is a metabolic liver disorder commonly attributed to fatty acid deposition that can induce hepatic necroinflammation, defined as nonalcoholic steatohepatitis (NASH). It is strongly associated with obesity. Laparoscopic sleeve gastrectomy (LSG) is a favorable surgical modality for the treatment of morbid obesity. AIM: Our study evaluated the impact of LSG on patients with NAFLD and morbid obesity, 3 months after the operation, through clinical and biochemical characteristics, clinico-biochemical indices, and imaging parameters. PATIENTS AND METHODS: Morbidly obese patients with NAFLD±NASH underwent LSG. They were thoroughly evaluated clinically (body weight, body mass index, waist circumference) and biochemically (transaminases and triglycerides), as well as through the fatty liver index (FLI), the hepatic steatosis index (HSI), and ultrasound elastography imaging studies (liver stiffness measurement [LSM] and the controlled attenuation parameter [CAP]), before and 3 months after the LSG. RESULTS: Twenty-six obese patients with NAFLD underwent LSG that resulted in a significantly high reduction in all the parameters analyzed, except for liver transaminases. CONCLUSION: LSG is considered an efficient surgical modality for the treatment of morbidly obese patients with NAFLD.

Study of cell mediated immune responsiveness to soluble egg antigen and phytohaemagglutinin using the lymphoblast transformation test in human schistosomiasis mansoni in Egypt.

Antigeno soluvel de ovo e fitohemaglutinina foram usados para medir a resposta imunologica celular dos pacientes com esquistossomose mansonica atraves do teste de transformacao linfoblastica. Antigeno soluvel de ovo mostrou resposta maior nos casos com hepatosplenomegalia quando comparados com as formas intestinais simples, as respostas mais altas sendo reencontradas nos grupos etarios mais jovens. Fitohemaglutinina mostrou resposta menor nos casos de esquistossomose intestinal simples e resposta maior nos grupos etarios de media idade. Esses resultados corroboram a importancia da resposta imunologica de tipo celular do hospedeiro nas varias manifestacoes da esquistossomose