1.
RSC Adv
; 14(8): 5542-5546, 2024 Feb 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38352680
RESUMO
Caerulomycins, natural alkaloids with antimicrobial properties, have been previously synthesized starting with highly pre-functionalized building blocks or requiring many functional group manipulations. In this work, we report the first total synthesis of caerulomycin K, a diversely trifunctionalized pyridine readily assembled in three steps exploiting the recent advancements in the C-H activation of N-heterocycles.