RESUMO
Objective:Delayed encephalopathy after acute carbon monoxide poisoning(DEACMP)is the most severe complication of carbon monoxide poisoning,which seriously endangers patients'quality of life.This study aims to investigate the efficacy of hyperbaric oxygen(HBO2)on improving dementia symptoms in patients with DEACMP. Methods:A retrospective analysis was performed on DEACMP patients,who visited Xiangya Hospital,Central South University from June 2014 to June 2020.Among them,patients who received conventional drug treatment combined with HBO2 treatment were included in an HBO2 group,while those who only received conventional drug treatment were included in a control group.HBO2 was administered once daily.Patients in the HBO2 group received 6 courses of treatment,with each course consisting of 10 sessions.The Hasegawa Dementia Scale(HDS)was used to diagnose dementia,and the Clinical Dementia Rating(CDR)was used to grade the severity of dementia for DEACMP.The Alzheimer's Disease Assessment Scale-Cognitive Section(ADAS-Cog),the Functional Activities Questionnaire(FAQ),the Neuropsychiatric Inventory(NPI),and the Clinician's Interview-Based Impression of Change-Plus Caregiver Input(CIBIC-Plus)were performed to assess cognitive function,ability to perform activities of daily living(ADL),behavioral and psychological symptoms,and overall function.The study further analyzed the results of objective examinations related to patients'dementia symptoms,including magnetic resonance imaging detection of white matter lesions and abnormal electroencephalogram(EEG).The changes of the above indicators before and after treatment,as well as the differences between the 2 groups after treatment were compared. Results:There was no significant difference in the HDS score and CDR grading between the 2 groups before treatment(both P＞0.05).After treatment,the score of ADAS-Cog,FAQ,NPI,and CIBIC Plus grading of the 2 groups were significantly improved,and the improvement of the above indicators in the HBO2 group was greater than that in the control group(all P＜0.05).The effective rate of the HBO2 group in treating DEACMP was significantly higher than that of the control group(89.47% vs 65.87%,P＜0.05).The objective examination results(white matter lesions and abnormal EEG)showed that the recovery of patients in the HBO2 group was better than that in the control group. Conclusion:Hyperbaric oxygen can significantly relieve the symptoms of dementia in patients with DEACMP.
RESUMO
Objective To give a clear definition of professional exposure to HIV and map out the preventive strategies. Methods To propose the preventive strategies for preventing professional exposure to HIV according to the relative knowledge and the practical nursing measures. Results The preventive strategies include the recognition from the administrative authority, care about the exposure suits for preventing HIV , the establishment of a reasonable by law, properly handling the wound when exposure happen and report the accident to local CDC and arrange HIV test at 4,8,12 week and 6 month after exposures. Conclusions The medical staff lack the knowledge of preventing professional exposure to HIV, the intensive training is urgently needed. It is better to involve the professional HIV exposure as one of the professional injuries by law in order to relieve the medical staff′s anxieties about HIV exposure during the course of working.
RESUMO
Objectives:To investigate the efficacy of STI/HIV preventive intervention on prostitutes and to discuss the ethical issues.Method:Anonymous questionnaire survey was used to collect the KAB data before and after health education. The data were analysed by using SPSS10.0 software. Results:140 prostitutes received health education and 87 prostitutes were evaluated after intervention.Both the condom knowledge and the condom use during sex increased significantly after health education(P
