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Int J Oral Maxillofac Surg ; 42(6): 759-64, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-23538215

RESUMO

The aim of the present study was to investigate the effect of botulinum toxin type A (BTX-A) injection in the lateral pterygoid (LP) muscle on temporomandibular joint (TMJ) clicking. The study enrolled seven patients with a total of 11 joints; all patients were stage I or II of Wilke's staging for internal derangement. BTX-A was injected in the ipsilateral LP muscle with electromyogram (EMG) guidance and the subjects were assessed for 4 months. Maximum inter-incisal opening, range of lateral movement, and the presence of a click were recorded throughout the follow-up period, and magnetic resonance imaging (MRI) was ordered at the end of the 4 months. The results showed that the decrease in inter-incisal opening and side to side movement immediately postoperative was statistically significant, while the difference by the end of the follow-up period was insignificant. MRI showed a marked improvement in disc position postoperatively. It may be concluded that BTX injection in the LP muscle leads to the disappearance of joint clicking clinically and a significant improvement in disc position as shown on MRI.


Assuntos
Antidiscinéticos/administração & dosagem , Toxinas Botulínicas Tipo A/administração & dosagem , Transtornos da Articulação Temporomandibular/tratamento farmacológico , Adulto , Análise de Variância , Eletromiografia , Feminino , Humanos , Injeções Intramusculares , Luxações Articulares/tratamento farmacológico , Imageamento por Ressonância Magnética , Masculino , Músculos Pterigoides , Amplitude de Movimento Articular/efeitos dos fármacos , Som , Disco da Articulação Temporomandibular/patologia , Adulto Jovem
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