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Transplant Proc ; 45(3): 1084-7, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-23622632

RESUMO

Diarrhea, which is common after transplantation, may be due to infections and immunosuppressive therapy. Inflammatory bowel disease (IBD) de novo or as an exacerbation of pre-existent disease is a rare complication after kidney transplantation with pre-existing disease having a less aggressive clinical course than the de novo disease. Cytomegalovirus mismatch, prescription of tacrolimus instead of cyclosporine or mycophenolate mofetil rather than azathioprine as well as low-dose corticosteroid treatments have been linked to an increased incidence of IBD. This series of renal transplant recipients with de novo IBD showed a higher incidence and more aggressive course than that previously described, possibly related to increased use of tacrolimus with minimization of steroids.


Assuntos
Imunossupressores/efeitos adversos , Doenças Inflamatórias Intestinais/induzido quimicamente , Transplante de Rim , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
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