[Breast cancer at present and 30 years ago]. / Rak molochnoi zhelezy v nastoiashchee vremia i 30 let nazad.

Comparison of the data on pathomorphosis of breast cancer and parameters of reproductive function of patients for 1983-1986 and 1953-1956 failed to establish increased aggressiveness of tumor during 30 years; however, the profile of factors influencing tumor development changed. At present, breast cancer is provoked by a longer and stronger estrogen stimulation; its duration has increased by 4.1 years which is an equivalent of more than 100 ovulatory cycles.