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BACKGROUND: Digital dentistry has revolutionized the field of implant dentistry, offering enhanced accuracy and precision in implant placement and prosthesis fabrication. This study aims to evaluate the effect of digital dentistry on the accuracy of implant placement and prosthesis fit through a comprehensive in-vitro assessment. METHODS: In this in-vitro study, a Digital Dentistry Group and a Conventional Group were compared regarding implant placement accuracy and prosthesis fit. Measurements of coronal deviation, apical deviation, global deviation, angulation deviation, and depth deviation were obtained for implant placement accuracy, while marginal fit and internal fit were assessed for prosthesis fit. Statistical analysis was performed to determine significant differences between the two groups. RESULTS: The Digital Dentistry Group demonstrated significantly lower values of coronal deviation, apical deviation, global deviation, angulation deviation, and depth deviation compared to the Conventional Group (p < 0.001). Similarly, the Digital Dentistry Group exhibited superior marginal fit and internal fit (p < 0.001) when compared to the Conventional Group. CONCLUSION: This in-vitro study provides evidence supporting the superior accuracy of implant placement and improved prosthesis fit achieved through digital dentistry techniques. The use of intraoral scanners, computer-aided design/computer-aided manufacturing (CAD/CAM) systems, and three-dimensional (3D) imaging enables precise digital impressions, virtual planning, and custom-made prostheses with superior fit and esthetics. Incorporating digital dentistry into clinical practice can enhance treatment outcomes and patient satisfaction in implant dentistry.
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Objective: The objective of the study was to use polymerase chain reaction (PCR) to examine and compare the genotype distribution of human papillomavirus (HPV) in oral lichen planus (OLP). Materials and Methods: Deoxyribonucleic acid (DNA) was extracted from 20 OLP biopsy specimens. Conventional PCR assay employing consensus HPV primers was used to identify HPV DNA. Positive PCR samples were then subjected to PCR assay with HPV type-specific primers. Results: Out of the total 20 OLP specimens evaluated, eight samples (40%) were positive for HPV. Females had a 41.7% higher HPV-positive rate than males. The most common type in the HPV type-specific PCR assay was HPV-18 (75%), which is a high-risk type of HPV linked to malignant diseases. The erosive kind of OLP had the greatest percentage of HPV positives (50%). Conclusion: The present study confirms the detection of HPV in OLP lesions, as determined by PCR-coupled HPV gene sequencing, as well as its likely mechanism of malignant transformation.
