Fabrication of Novel 3-D Nanocomposites of HAp-TiC-h-BN-ZrO2: Enhanced Mechanical Performances and In Vivo Toxicity Study for Biomedical Applications.

Due to excellent biocompatibility, bioactivities, and osteoconductivity, hydroxyapatite (HAp) is considered as one of the most suitable biomaterials for numerous biomedical applications. Herein, HAp was fabricated using a bottom-up approach, i.e., a wet chemical method, and its composites with TiC, h-BN, and ZrO2 were fabricated by a solid-state reaction method with enhanced mechanical and biological performances. Structural, surface morphology, and mechanical behavior of the fabricated composites were characterized using various characterization techniques. Furthermore, transmission electron microscopy study revealed a randomly oriented rod-like morphology, with the length and width of these nanorods ranging from 78 to 122 and from 9 to 13 nm. Moreover, the mechanical characterizations of the composite HZBT4 (80HAp-10TiC-5h-BN-5ZrO2) reveal a very high compressive strength (246 MPa), which is comparable to that of the steel (250 MPa), fracture toughness (14.78 MPa m1/2), and Young's modulus (1.02 GPa). In order to check the biocompatibility of the composites, numerous biological tests were also performed on different body organs of healthy adult Sprague-Dawley rats. This study suggests that the composite HZBT4 could not reveal any significant influence on the hematological, serum biochemical, and histopathological parameters. Hence, the fabricated composite can be used for several biological applications, such as bone implants, bone grafting, and bone regeneration.

Synergetic effects of boron nitride with waste zirconia: Evaluation of instantaneous fingerprint detection and mechanical properties for biomedical applications.

Herein, present study mainly focuses on the synthesis and characterizations of boron nitride reinforced waste zirconia (wZrO2) with different concentrations. Composites were prepared via a scalable solid-state reaction method. Various physical parameters such as density, ionic concentration, polaron radius, and field strength were evaluated. XRD results reveal crystalline nature with a major phase of tetragonal zirconia and as boron nitride is reinforced, the tetragonal transforms into a monoclinic zirconia. Interconnected spherical grains and nanosheets were observed using FESEM. Mechanical characterizations revealed the highest compressive strength of 266 MPa. The latent fingerprints were visualized using a composite on different surfaces, implementing the powder dusting and solution techniques. MTT assay was performed and revealed good biocompatible nature. These results reveal that composite is suitable for fabrication of bioceramics with acceptable mechanical and biological performances. The composite can also be utilized for latent fingerprint detection in forensic science.

Synthesis of a porous SiO2-H3BO3-V2O5-P2O5 glassy composite: structural and surface morphological behaviour for CO2 gas sensing applications.

The present work mainly focuses on the fabrication of a porous glass 40SiO2-35H3BO3-19V2O5-6P2O5 via a melt-quenching technique. The structural, morphological, and sensing behaviour of the glass sample was investigated successfully. The calculated density and molar volume of the fabricated glass are 2.4813 ± 0.124 g cm-3 and 35.7660 ± 1.708 cm3 mol-1. XRD, SEM and TEM analyses confirmed the amorphous nature of the glass. FTIR results revealed the O-H bond formations, which indicate that the presence of water molecules is probably due to the porous nature of the glass. Further, BET analysis confirmed the mesoporous nature of the glass sample with a mean pore diameter of 7 nm. The sensing response of the synthesized glass at 1000 ppm concentration of CO2 was found to be 3.05 with a response time 22.6 s and recovery time 25.8 s. Hence, this porous glass can be easily synthesized, is affordable, and was found to be useful for CO2 gas sensing applications.