Assuntos
Cárdia/cirurgia , Acalasia Esofágica/cirurgia , Esôfago/cirurgia , Adolescente , Adulto , Criança , Esofagoscopia , Feminino , Humanos , Masculino , Métodos , Pessoa de Meia-Idade , NigériaRESUMO
Recent interest in vascularity in relation to peptic ulceration poses the question of relationship between three entities: (1) site of gastro-jejunal (post-anastomotic) ulcer, (2) site of the anastomotic line and (3) site of junction and possible vascular anastomosis between gastric and jejunal circulations in the region of the anastomosis. Vascular injection studies in dogs show that the main gastric and jejunal circulations run up to, but do not communicate across, the surgical anastomosis, there being a line of least vascularity at the anastomosis. Since anastomotic ulcers occur distal to the anastomotic line, this supports the view that such ulcers are situated wholly in an area of jejunal circulation.
Assuntos
Jejuno/irrigação sanguínea , Estômago/irrigação sanguínea , Animais , Cães , Feminino , Jejuno/cirurgia , Masculino , Úlcera Péptica/etiologia , Estômago/cirurgiaRESUMO
The prophylactic value of gentamicin combined with either lincomycin or metronidazole in 52 patients undergoing colorectal surgery was investigated. The results confirmed the value of this practice. In a control group, the sepsis-rate was 48% with 1 death attributable to sepsis, compared with a sepsis-rate of 4% in the treated group. The combination of gentamicin and lincomycin was effective against sepsis but pseudomembranous colitis developed in 2 of the 14 patients treated with this combination of drugs. Lincomycin was discontinued, and when metronidazole was substituted the results were equally good and there were no toxic side-effects.