Assuntos
Hiperplasia Prostática , Obstrução do Colo da Bexiga Urinária , Bexiga Urinária , Humanos , Masculino , Hiperplasia Prostática/complicações , Hiperplasia Prostática/patologia , Hiperplasia Prostática/fisiopatologia , Bexiga Urinária/irrigação sanguínea , Bexiga Urinária/patologia , Bexiga Urinária/fisiopatologia , Obstrução do Colo da Bexiga Urinária/etiologia , Obstrução do Colo da Bexiga Urinária/patologia , Obstrução do Colo da Bexiga Urinária/fisiopatologiaRESUMO
Experiments on 8 rabbits have demonstrated that mucosa of the urinary bladder freely transplanted into the subcutaneous fat or under the muscular fascia is engrafted with unaffected normal histological structure and revascularized with vessels invading from the adjacent tissues. Urethroplasty with a vesical mucosa graft was made in 10 dogs with experimental urethral stricture (4 animals), urethral fistula (5 animals) or a combination of urethral stricture and fistula (1 animal). A positive result with reestablishment of normal urethral passability and elimination of urinary fistula was achieved in 9 animals (followup for 1 year). One dog died of an unknown cause. Urodynamic examination of the dogs in long-term follow-up reported normal urethral resistance to urinary flow.
Assuntos
Procedimentos de Cirurgia Plástica/métodos , Transplante de Tecidos/métodos , Uretra/cirurgia , Bexiga Urinária/cirurgia , Bexiga Urinária/transplante , Animais , Cães , Mucosa/cirurgia , Mucosa/transplante , Coelhos , Radiografia , Transplante Autólogo , Transplantes , Uretra/diagnóstico por imagem , Fístula Urinária/cirurgiaRESUMO
The experiments on 15 dogs with preformed urethral stricture or urinary urethral fistula have demonstrated that microsurgical transplantation of the vascular fasciocutaneous pedicle flap provides good functional long-term results. The best effect was achieved in cases of intraflap inclusion of previously transplanted mucosa of the urinary bladder. In all 7 experiments x-ray picture was similar to normal. Recurrent strictures or urethral fistulas were not registered. Urodynamic indices late after the experiment did not differ significantly from normal values.