[Features of fetal development in a woman with uterus duplex].

Moderate doses of radiation exposure in the early period of embryogenesis may become the reason of occurrence of uterus duplex and raise a follicular unit ovarian the future girl of that predetermines a high probability of malformations of the fetus during future pregnancies after reaching adult age.

[Investigation of the level of genetical safety of urban population].

As it is universally recognized, the population is a sound criteria of the environment quality. The most reliable method to evaluate genetic processes in a population under the condition of the environmental pollution is genetic monitoring, a survey of dynamic parameters of genetic load. An evaluation of genetical safety of an urbanized area of a city is represented in this article. The parameters of genetic load like congenital malformations and multifactorial diseases have been used in the models of monitoring. The analysis and comparison of disease frequencies in Kharkiv Dzerzhinsky District, in other European populations and in regional rural districts with various levels of production have been made.

[Genetic study of psoriasis in the Kharkov population]. / Geneticheskoe izuchenie psoriaza v khar'kovskoi populiatsii.

By means of genetic analysis of 400 individuals suffering from psoriasis the mendelian inheritance model have been rejected: the segregation frequencies are SFNxN = 0.083 and SFNxA = 0.1474. The heritability of psoriasis in the polygenic model is about 100%. The main gene model with incomplete penetration have been proposed (p = 0.044, [symbol: see text]1 = 6.1%, [symbol: see text]2 = 82.2%). 0.189% residents of Kharkov population are homozygotes and 8.32% heterozygotes on psoriatic gene, 0.155% residents are suffering from psoriasis heterozygotes and 0.508% heterozygotes. Among individuals suffering from psoriasis 23% are homozygotes and 77% heterozygotes.