[Roadmap for ecosystem-based approach for patients with Alzheimer disease in Russia: current needs, barriers, and possible solutions (resolution of the scientific and practical experts meeting)]. / Dorozhnaya karta po okazaniyu pomoshchi patsientu s bolezn'yu Al'tsgeimera v Rossii v formate ekosistemy: tekushchie potrebnosti, bar'ery i vozmozhnye resheniya (rezolyutsiya nauchno-prakticheskoi vstrechi ekspertov).

The care of a patient with Alzheimer's disease (AD) is considered from the perspective of an ecosystem, that is, a systemic approach describing effective partnership, collaboration and research aimed at creating value, involving all participants in the AD patient journey. The effectiveness of this ecosystem is only possible with the involvement of all stakeholders in its development, including patients, healthcare professionals at all levels, government agencies, private companies, and patient organizations. The unmet health care and information needs of patients with AD are a consequence of barriers in the AD ecosystem. Key barriers for the patient include low awareness and stigmatization of the disease in society, lack of quality epidemiological data, difficulties in timely diagnosis, lack of prevention programs, unpreparedness of most physicians to conduct AD patient rehabilitation, and other factors. Based on the analysis of the ecosystem of AD and the patient pathway, 10 main directions (strategies) necessary for the formation of the ecosystem were identified: conducting research in the diagnosis and epidemiology of AD, creating and implementing a cognitive health program, forming a legal framework, raising public awareness, optimizing patient routing for timely diagnosis, organizing a network of memory clinics/laboratories, creating a register of patients with dementia, developing digital solutions and supporting social projects.

ATHEROSCLEROSIS OF ABDOMINAL AORTA IN A POPULATION OF THE NORTHERN PART OF EUROPEAN RUSSIA.

Atherosclerosis is a major challenge for public health services throughout the world. It is a systemic degenerative disease affecting all arterial basins and most fiequently occurring in men aged above 40 years. Multifocal lesions are much more typical than isolated lesion of a single basin. Atherosclerosis is a frequent cause of impaired patency of visceral branches of abdominal aorta and is a chronic disorder of visceral circulation manifest as ischemia of abdominal organs. We studied native preparations of abdominal aortafrom residents of the northern part of European Russia using the WHO-recommended visual planimetric method. It was shown that 93.4% of the residents of this region aged above 50 years have abdominal aorta affected by atherosclerosis. Statistical analysis did not reveal signficant differences between the frequency of atherosclerotic lesions in men and women. Most of them had raised aortic lesions. Correlation analysis with the calculation ofpaired Pearson correlation coefficients demonstrated moderate correlation between atherosclerotic lesions of abdominal aorta and the stage of atheromatosis (r=0,42; p = 0,000).